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H2020Doctoral network2015–2018

MULTI-APP · Multivalent Molecular Systems for Innovative Applications

Horizon 2020 — Marie Skłodowska-Curie Actions

Duration
2015-01-01 → 2018-12-31
EU contribution
€2,321,096
Participants
9
Scheme
MSCA-ITN-ETN

Lines connect the coordinator with its partners.

Results in brief

Multivalent Molecular Systems for Innovative Applications

This network brings together the major academic research groups in Europe dealing with the fundamentals and applications of multivalency and cooperativity. The network is complemented by industrial partners that contribute to the training programme. The main objective of this consortium is to raise a new generation of researchers able to develop complex chemical systems that harness cooperativity for enhanced functional properties. Multivalency is one of Nature’s governing principles for achieving strong and selective biomolecular recognition. Many biological processes rely on the cooperative effects associated with the occurrence of multivalent interactions. Consequently, there is an enormous interest in the development of chemical multivalent systems that display similar features for innovative applications in fields as various as diagnostics, drug discovery, materials science and nanotechnology. In order for Europe to be at the front wave of this development, it needs to invest now in young researchers that understand how cooperativity works in multivalent systems, that are experts in preparing and characterising a wide variety of multivalent systems, and that are acquainted with the fundamentals, challenges and also the limitations of different applications. The central theme of multivalency and cooperativity is used to connect partners from academia and industry with a common interest in understanding how multivalency works, but for very different scopes and using very different approaches. This network is thus uniquely positioned to train the next generation of European researchers in all multidisciplinary aspects related to multivalency. A broad training programme has been developed that comprises top-level individual research projects, both general and specific network-wide dedicated courses, secondments, personalized scientific training and a broad package of complementary skill training. During the project, various industrial partners have contributed in the form of training, technical contributions, and perspectives on the commercialisation of multivalent systems.

Data: CORDIS, © European Union

Project objective

This network brings together the major academic players active in Europe on the fundamentals and application of multivalency and cooperativity. The network is complemented by industrial partners ranging in scale from a small spin-off to a large multinational. The main objective of this consortium is to raise a new generation of researchers able to develop complex chemical systems that harness cooperativity for enhanced functional properties.Multivalency is one of Nature’s governing principles for achieving strong and selective biomolecular recognition. Many biological processes rely on the cooperative effects associated with the occurrence of multivalent interactions. Consequently, there is an enormous interest in the development of chemical multivalent systems that display similar features for innovative applications in fields as various as diagnostics, drug discovery, materials science and nanotechnology.The central theme of multivalency and cooperativity is used to connect partners from academia and industry with a common interest in understanding how multivalency works, but for very different scopes and using very different approaches. This network is thus uniquely positioned to train the next generation of European researchers in all multidisciplinary aspects related to multivalency. A broad training program has been developed that comprises top-level individual research projects, both general and specific network-wide dedicated courses, secondments, personalized scientific training and a broad package of complementary skill training. The industrial partners contribute in the form of training, supervision, technical contributions, and perspectives on the commercialisation of multivalent systems.After completion of the program, the ESRs will be the first generation of researchers able to fully exploit the potential of multivalent chemical systems. Their unrivalled career profiles will enable them to compete successfully for positions in academia or industry.

Original text from CORDIS.

Participants

  • UNIVERSITA DEGLI STUDI DI PADOVA · PadovaCoordinatorItaly
  • FREIE UNIVERSITAET BERLIN · BerlinGermany
  • PHILIPS ELECTRONICS NEDERLAND BV · EindhovenNetherlands
  • TECHNISCHE UNIVERSITEIT EINDHOVEN · EindhovenNetherlands
  • THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE · CAMBRIDGEUnited Kingdom
  • THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD · OxfordUnited Kingdom
  • UNIVERSITAET MUENSTER · MuensterGermany
  • UNIVERSITEIT TWENTE · EnschedeNetherlands
  • mivenion GmbH · BerlinGermany

Links

Data: CORDIS, © European Union