H2020Individual fellowship2016–2018

E-SPACE · European Standardised Process Approach to Cognitive Evaluation in older people

Horizon 2020 — Marie Skłodowska-Curie Actions

Duration
2016-02-01 → 2018-01-31
EU contribution
€187,866
Participants
1
Scheme
MSCA-IF-EF-ST

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Results in brief

European Standardised Process Approach to Cognitive Evaluation in older people

Background: Cognitive evaluation is important for early and accurate dementia diagnosis. However, currently available cognitive tests, particularly brief screening tests, are not always reliable in detecting the earliest stages of cognitive decline. This project aimed to improve current measures, using a process-based approach to cognitive assessment, as cognitive testing will be incomplete if it relies on summary scores alone and does not take account of other aspects of test performance. Typically, cognitive evaluation pays attention only to “what” one does (i.e. test scores). Above a certain score or cut-point (e.g. ≥24/30), the person may be considered “healthy” and below that cut-point (≤23) there could be suspicion of cognitive deterioration. However, people with high education levels may perform above the cutoff and look “healthy” when they may not be and people with low education levels may perform poorly despite being cognitively healthy. Misclassification can result in failure to detect deterioration or in classifying someone as impaired when they are not. Both scenarios highlight the need to improve tests to ensure early and proper diagnosis. Importance for society: The benefits of early and accurate diagnosis of Mild Cognitive Impairment and/or dementia include the fact that the person may still be able to participate actively in care planning and in decision-making about important issues like drug treatments, legal and financial affair management and service options. Early and correct diagnosis can also enable the person and family members to adjust and adapt. This may improve quality of life and reduce stress. Furthermore, at a societal level, timely diagnosis can reduce healthcare costs by delaying nursing home admission. Project objectives: The main goal of this project was to review existing screening tests and, where possible, to improve those measures to provide clinicians with better tools for early and accurate diagnosis. Conclusions of the Action: We identified and developed two test batteries that allow clinicians perform a brief cognitive assessment. Tests are administered in the usual manner, but the clinician now pays attention to the person’s answers and registers them verbatim so that answers and errors can be examined in detail.

Data: CORDIS, © European Union

Project objective

During this fellowship at Dublin City University (Ireland), the researcher will enhance, significantly, the clinical utility of existing traditionally used cognitive tests, particularly as it relates to the early detection and accurate diagnosis of mild cognitive impairment (MCI) and dementia. Cognitive difficulties represent the hallmark of many neurodegenerative conditions and, in relation to dementia, cognitive evaluation represents one major pillar of current methods of detection and diagnosis. There are, however, many difficulties with existing cognitive tests and this project has been designed to address this issue. The need for and the potential benefits of early and accurate detection of MCI and dementia is well-recognised. Early and accurate detection is, however, complex and, at present, is subject to high diagnostic error rates. With the expected advent of new effective drug treatments for different neurodegenerative diseases (e.g. Alzheimer’s disease), early and accurate diagnosis will be even more vital into the future. Using the principles of what is known as the Qualitative Process Approach (QPA), the goal of this project is to identify and develop a battery of cognitive tests, both in traditional paper-and-pencil form and, when clinically appropriate, in a computerised version, with the aim of enabling a wide range of clinicians improve early and accurate diagnosis. This fellowship will play a crucial role in the career of Dr. Unai Diaz Orueta by providing him with international research experience and making him a reference expert in international neuropsychological research. Patients, families and society will benefit for earlier detection, earlier intervention, and reduced healthcare costs, as the improvement in the accuracy of the diagnosis of neurodegenerative conditions will subsequently impact in planning appropriate early interventions and saving millions of Euros associated to both formal and informal care of older people with dementia.

Original text from CORDIS.

Participants

  • DUBLIN CITY UNIVERSITY · DublinCoordinatorIreland

Links

Data: CORDIS, © European Union