MONSTAA · Metabolism of Novel Strains of Arctic Algae
Horizon 2020 — Marie Skłodowska-Curie Actions
- Duration
- 2017-09-01 → 2020-04-30
- EU contribution
- €231,642
- Participants
- 2
- Scheme
- MSCA-IF-GF
Lines connect the coordinator with its partners.
Results in brief
Metabolism of Novel Strains of Arctic Algae
As the world’s population grows and natural resources diminish it is essential to secure more sustainable sources of food and energy whilst reducing our impacts on the environment. Agricultural production systems must become more efficient, and recycling waste materials is a priority for the modern bio-based economy. Microalgae, single-celled photosynthetic organisms, are a promising new source of food and feed ingredients. Algae are capable of very high growth rates, can make use of waste or saline water supplies, reduce industrial CO2 emissions, and can be produced on non-arable land. Industrial microalgae cultivation in bioreactors or open ponds offers promising solutions to global food, climate and energy issues, but producing algal biomass at scale with low environmental impacts still faces challenges. Recent studies have highlighted key bottlenecks in the large-scale production of microalgae-based materials, including the amount of energy that must be invested in cultivation, and the need to develop new industrial strains with higher product yields. In nature there are a great diversity of microalgae species with features including the ability to grow in extreme environments, produce valuable lipids, natural pigments or novel hydrocarbons (oils). Microalgae are especially an excellent source of omega-3 fatty acids including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). These compounds are of special interest, because they are essential components in the diets of humans and farmed fish that are usually sourced from unsustainable marine capture-fisheries. To turn new wild-type algae into efficient single-cell factories requires deep understanding of their behavior and metabolism for the rational design and control of production strains and their cultivation systems. The objective of this project is to investigate metabolic networks in novel microalgae that offer e.g. high yields of oil and omega-3 fatty acids. A particular focus is placed on coldwater varieties, which could offer unique genetic innovations and specific adaptations to harsh environmental conditions. The main focus of my research is establishing genomic data and models to work with new species, so that they may be applied at larger scale in raceway ponds or industrial bioreactor systems.
Data: CORDIS, © European Union
Project objective
Due to increasing environmental and economic pressures, there is a need to develop more efficient and sustainable food, feed and fuel production systems. Microalgae have substantial potential as single-cell molecular factories for producing high quality lipids, proteins and carbohydrates. They are capable of faster growth rates than crop plants and synthesize valuable metabolites that do not occur naturally in other primary producers. However, a major bottleneck that currently limits widespread microalgae production are the low yields achieved by commercial strains in cold climates. This project will develop new varieties of microalgae isolated from Arctic and Antarctic environments for applied bioprocesses. The work will include studying the metabolism of novel microalgae in low temperature bioreactors using functional genomics. The researcher will spend the outgoing phase at an established microalgae metabolism laboratory in the USA, where complete and very high quality training will be given in cutting-edge Next Generation Sequencing (NGS) technology. Genomic and transcriptomic work will be paired with metabolomics to give new insights into the regulation of metabolism in non-model microalgae species. The research will also include integrating data together into metabolic flux model frameworks. The major research outcomes will be (1) Genome-scale characterization of brand-new varieties of microalgae (2) Development of novel microalgae bioprocesses for high yields of lipids, proteins and carbohydrates in cold climates (3) Predictive metabolic models for maximizing yields of products of interest in non-model varieties of microalgae. In addition, comprehensive work and dissemination plans are presented that will target scientists, industry and the public.
Original text from CORDIS.
Participants
- NORD UNIVERSITET · BODOCoordinatorNorway
- COLORADO SCHOOL OF MINES · GoldenUnited States
Links
- View on CORDIS
- DOI: 10.3030/749910
- https://www.nord.no/en/news-events/news/Pages/EU-fellowship-to-young-Nord-researcher.aspx
Data: CORDIS, © European Union
