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H2020Doctoral network2018–2021

PhotoBioCat · Light-driven sustainable biocatalysis training network

Horizon 2020 — Marie Skłodowska-Curie Actions

Duration
2018-01-01 → 2021-12-31
EU contribution
€3,029,067
Participants
19
Scheme
MSCA-ITN-EJD

Lines connect the coordinator with its partners.

Results in brief

Light-driven sustainable biocatalysis training network

Pharmaceutical and chemical products present in everyday life are currently obtained from waste- and energy-intensive processes. Alternative routes that overcome this challenge should offer a cleaner and long-lasting solution. PhotoBioCat aimed at developing efficient and sustainable light-driven enzyme-catalyzed chemical processes to a commercial industrial level. The PhotoBioCat trained 12 early-stage researchers (ESRs) in cutting edge research projects on (i) the development of chemical and biological catalytic systems for the synthetic use of visible light for the production of pharmaceuticals, bulk-, fine- and specialty chemicals, (ii) up-scaling and optimization of commercially relevant processes together with industry, (iii) defining a road-map for the industrial implementation of photobiocatalysis. A double degree program allowed in-depth training in two complementary disciplines, further strengthened by a transferable skills training with strong industry participation. A consortium of seven universities and eight industrial partners provided a fruitful environment to foster complementary expertise in chemical synthesis, biocatalysis, synthetic biology and process engineering. PhotoBioCat thus explored (a) the catalytic application of photosynthetic microorganisms and their optimization by modern synthetic biology techniques; (b) the coupling of enzymes to light-harvesting molecules in vitro; and (c) the optimization of photobiocatalytic processes to technical scale; accompanied by specially designed training of the ESRs and dissemination & communication of the results to the scientific community and public.

Data: CORDIS, © European Union

Project objective

Pharmaceutical and chemical products present in everyday life are currently obtained from waste- and energy-intensive processes. Alternative routes that overcome this waste challenge should offer a cleaner and long-lasting solution. PhotoBioCat aims at developing efficient and sustainable light-driven enzyme-catalyzed chemical processes to a commercial industrial level. The PhotoBioCat EJD will train 12 ESRs in cutting edge research projects on (i) the development of chemical and biological catalytic systems for the synthetic use of visible light for the production of pharmaceuticals, bulk-, fine- and specialty chemicals, (ii) up-scaling and optimization of commercially relevant processes together with industry, (iii) defining a road-map for the industrial implementation of photobiocatalysis. The double degree program allows in-depth training in two complementary disciplines, further strengthened by a transferable skills training with strong industry participation.The objectives will be attained through a consortium of seven universities and eight industrial partners, providing the ideal environment to foster complementary expertise in chemical synthesis, biocatalysis, synthetic biology and process engineering. PhotoBioCat will explore (a) the catalytic application of photosynthetic microorganisms and their optimization by modern synthetic biology techniques; (b) the coupling of enzymes to light-harvesting molecules in vitro; and (c) the optimization of photobiocatalytic processes to technical scale; accompanied by specially designed training of the ESRs and dissemination of the results to scientific community and public.The inter- and multidisciplinary setting offered through double degrees combined with industrial training and set-ups will not only provide the tools and means necessary for the implementation of sustainable processes, but also prepare the next generation of researchers for for the implementation of sustainable processes in the Biotech sector.

Original text from CORDIS.

Participants

  • TECHNISCHE UNIVERSITAET GRAZ · GrazCoordinatorAustria
  • AARHUS UNIVERSITET · Aarhus CDenmark
  • ARKEMA FRANCE SA · PUTEAUX, LA DEFENSEFrance
  • CHIRACON GMBH · LuckenwaldeGermany
  • DANMARKS TEKNISKE UNIVERSITET · Kongens LyngbyDenmark
  • ENTRECHEM SL · OVIEDOSpain
  • GLAXOSMITHKLINE RESEARCH & DEVELOPMENT LIMITED · LONDONUnited Kingdom
  • Innophore GmbH · GrazAustria
  • RIJKSUNIVERSITEIT GRONINGEN · GroningenNetherlands
  • RUHR-UNIVERSITAET BOCHUM · BochumGermany
  • SANDOZ GMBH · KundlAustria
  • SIMRIS BIOLOGICS GMBH · BerlinGermany
  • SUBITEC GMBH · STUTTGARTGermany
  • TECHNISCHE UNIVERSITAT HAMBURG · HamburgGermany
  • TECHNISCHE UNIVERSITEIT DELFT · DelftNetherlands
  • UNIVERSIDADE DO PORTO · PortoPortugal
  • UNIVERSITAET GRAZ · GrazAustria
  • UNIVERSITE D'AIX MARSEILLE · MarseilleFrance
  • WAGENINGEN UNIVERSITY · WageningenNetherlands

Links

Data: CORDIS, © European Union