Menu
MapConnectionsTopicsBulgariaThe Night (K-TRIO)Marie Skłodowska-CurieFor studentsFor teachersMethodologySurprise me
H2020Doctoral network2017–2022

M-GATE · Memory research: Ground-breaking, Applied, and Technological Exchanges

Horizon 2020 — Marie Skłodowska-Curie Actions

Duration
2017-10-01 → 2022-03-31
EU contribution
€3,961,160
Participants
11
Scheme
MSCA-ITN-ETN

Lines connect the coordinator with its partners.

Results in brief

Memory research: Ground-breaking, Applied, and Technological Exchanges

In relation to its limited volume, the hippocampus is probably the most sophisticated piece of technology human beings carry along. The hippocampus is a small structure tucked deep inside the temporal lobes of our brain, which is critical to our ability to form memories for the events of our lives. Understanding the hippocampus is socially and economically important because when damaged, the hippocampus contributes to making life miserable in several pathologies. After migraine, epilepsies and Alzheimer disease are the most common neurological disorders. Temporal Lobe Epilepsy is the most common form of epilepsy in adults, is drug-resistant in 30% of the cases and is associated with co-morbidities, including cognitive deficits. Both disorders represent a huge cost to society estimated at 1.2% of world GDP. Hence, there is a clear need for further knowledge and treatment options for disorders affecting the functioning of the hippocampus. In line with this assessment, there is a great need for future experts in the field that have been trained and have developed unique multidisciplinary skills combining physiology, molecular biology, computational skills and micro-engineering in an interdisciplinary setting.

Data: CORDIS, © European Union

Project objective

In M-GATE, ESRs will combine state-of-the art experimental neurophysiology, innovative technologies, and advanced theoretical approaches to unveil memory mechanisms, from single neurons to brain networks, to cognition and behaviour, addressing the healthy and diseased brain. Through research and training from top-class scientists and close interaction with industrial partners, ESRs will develop unique multi-disciplinary skills combining physiology, molecularbiology, computation, micro-engineering, and entrepreneurshipThe exploration of the hippocampal formation and its role in memory is one of the great success stories of neuroscience. For no other structure have neuroscientists achieved such an in-depth knowledge of structure and mechanisms, making this field one of the most promising for breakthroughs in understanding human cognition. Our program will include world-leading, Europe- and US-based scientists in academic institutions as well as pharmaceutical, neurotechnological and machine learning companies, with the task of developing new technologies to understand memory and advance our chances to cure brain pathologies.Early-stage researchers will participate in scientific programs spanning hippocampus research broadly, from local circuital interactions at one brain site, to global networks including multiple brain structures. Dedicated projects will look at brain pathologies as epilepsy and Alzheimer’s from the circuits point of view. A neurotechnology work package spanning multiple projects will include novel methodological developments, bringing together academic and private sector technologists. With the help of targeted secondments and a tailored training program, we provide a unique opportunity for talentedresearchers to prepare for a career in either academic research or the private sector.

Original text from CORDIS.

Participants

  • STICHTING RADBOUD UNIVERSITEIT · NijmegenCoordinatorNetherlands
  • ATLAS NEUROENGINEERING BVBA · LEUVENBelgium
  • Google DeepMind · LondonUnited Kingdom
  • INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE · ParisFrance
  • Inscopix, Inc. · Palo AltoUnited States
  • JANSSEN PHARMACEUTICA NV · BeerseBelgium
  • NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU · TrondheimNorway
  • SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI DI TRIESTE · TriesteItaly
  • UNIVERSITE D'AIX MARSEILLE · MarseilleFrance
  • UNIVERSITY COLLEGE LONDON · LondonUnited Kingdom
  • WEIZMANN INSTITUTE OF SCIENCE · RehovotIsrael

Links

Data: CORDIS, © European Union