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H2020Doctoral network2018–2023

BioMedaqu · Aquaculture meets Biomedicine: Innovation in Skeletal Health research.

Horizon 2020 — Marie Skłodowska-Curie Actions

Duration
2018-08-01 → 2023-01-31
EU contribution
€3,747,204
Participants
9
Scheme
MSCA-ITN

Lines connect the coordinator with its partners.

Results in brief

Aquaculture meets Biomedicine: Innovation in Skeletal Health research.

Skeletal deformities are intensively studied in aquaculture due to their impact on product quality, while skeletal pathologies are a major issue in human medicine in an aging population. The basic aim of this project is to combine the expertise in skeletal biology of two separate fields, aquaculture studying large fishes and biomedicine using small model species, to the benefit of each specialty. A very diverse Consortium addressed the scientific objectives: 1. Deeper comprehension of interaction between physical drivers/nutritional factors and skeletal processes. 2. New insights into the use of model fish as a tool for vertebrate skeletal biology. 3. Deeper multilevel comprehension of skeletal processes in vertebrates.

Data: CORDIS, © European Union

Project objective

Skeletal anomalies in farmed fish are a continuous problem for global aquaculture, affecting fish welfare, performance, and product quality. Aquaculture research has made considerable progress in reducing the incidence of deformities, but new species, intensified production, the damned for sterile fish, delicate early life stages and new fish feed ingredients are a continuous challenge. The use of zebrafish (Danio rerio) and medaka (Oryzias latipes) as models for research into human skeletal diseases such as osteoporosis, osteopetrosis and degenerative joint diseases is increasing, however their potential as models for farmed fish has not been sufficiently explored. These models offer the possibility to obtain deeper insights into the fundamental mechanisms that can cause skeletal malformations in humans and in farmed fish. A framework for communication and scientific exchange between the aquaculture and biomedical sectors would benefit all stakeholders and advance scientific understanding of the problem. We propose a joint inter-sectorial training network to increase the mobility and visibility of scientists between aquaculture research and the biomedical sector using small fish models. The proposed ESR programs will provide career development to young researchers in the field of skeletal biology through international and multidisciplinary training on innovative molecular, histological, biochemical and cell culture methodologies relevant to both sectors. The network combines stakeholders from 7 European Universities, a US research hospital, and one Biological Institute. Commercial interests are represented by two Economy departments, one aquaculture and a major fish feed production company. This structure allows the flow of information and people between the biomedical and aquaculture sectors, and between academic and applied sectors, thus addressing several objectives of the Europe 2020 strategy and ensuring a direct route from knowledge to application.

Original text from CORDIS.

Participants

  • UNIVERSITE DE LIEGE · LIEGECoordinatorBelgium
  • INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE · ParisFrance
  • INSTITUTO PORTUGUES DO MAR E DA ATMOSFERA,IP · LISBOAPortugal
  • UNIVERSIDAD DE LAS PALMAS DE GRAN CANARIA · Las Palmas De Gran CanariaSpain
  • UNIVERSIDADE DO ALGARVE · FaroPortugal
  • UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA · RomaItaly
  • UNIVERSITA POLITECNICA DELLE MARCHE · AnconaItaly
  • UNIVERSITAET MUENSTER · MuensterGermany
  • UNIVERSITEIT GENT · GentBelgium

Links

Data: CORDIS, © European Union