MCRD · Development Of Microfluidic Based Low Cost Industrial Cryo-Ready Devices For Preservation Of Living Cells
Horizon 2020 — Marie Skłodowska-Curie Actions
- Duration
- 2020-03-01 → 2022-09-30
- EU contribution
- €196,708
- Participants
- 1
- Scheme
- MSCA-IF
Lines connect the coordinator with its partners.
Results in brief
Development Of Microfluidic Based Low Cost Industrial Cryo-Ready Devices For Preservation Of Living Cells
The increased demand for cell therapy products requires that the World Health Organisation issue new regulations for the clinical storage and applications of these developed products. An immediate need is to create research and infrastructure for the long-time storage of the products. Current processes such as cryopreservation, lyophilisation and desiccation are highly toxic for cell viability. The EU-funded MCRD project is proposing a collaboration with French company Eden Tech to develop a microfluidic-based cryo-ready device for plug-and-play type biological cell sample storage and testing. The novel product will pave the way for further advanced studies into physical biology.
Data: CORDIS, © European Union
Project objective
Innovation in development of cell therapy products are growing rapidly. As per the report of WHO, in the year 2015, total 38 such innovation has been taken place in EU region and other developed countries. Such accelerated growth of the technology leads WHO to configure regulatory issues for the clinical storage and applications of these developed products. Thus, on the basis of current requirements, there is a immediate need to develop systemic research and infrastructure for storage of the developed biological products for longer duration of time. Cryopreservation, lyophilization, and desiccation are the major techniques been used for the preservation of biological products, namely different types of cells. But all above mentioned process are highly toxic while considering cellular viability. At the same time, this processes are bulky and involves substantial cost affair. In current project proposal, ER in collaboration with Eden Microfluidics have proposed development of a microfluidic based cryo-ready device for plug-and-play type cell / biological sample storage, testing, and laboratory usage. The proposed technique is highly inter-disciplinary, and with the experience of ER and his mentors from Eden Microfluidics, they are confident for the development of the product. The development of the product will yield new insight of physical biology in the field of magneto-hydrodynamics, biological thermodynamics, and bio-microfluidics. The proposed project is not only limited to the development of product, but it will extend the work for marketing and production of the product, and dissemination of the acquired field of science to the national and international universities as text contents (in form of book chapters), laboratory tutorials through the collaborations of ER. The developed cryo-ready microfluidic device will also foster ER for involve in EU region as a start-up, and thus contribute to the economical growth of the region directly.
Original text from CORDIS.
Participants
- EDEN TECH · ParisCoordinatorFrance
Links
Data: CORDIS, © European Union