STIMOS · Stimulation of Multiple Organoids Simultaneously

Stimulation of Multiple Organoids Simultaneously

Visual impairment affects approximately 26 million Europeans (WHO 2010): 2.5 million of these people are blind and 23.8 million have reduced vision. In France, Germany, Italy, and the UK the estimated cost for treatment is €47 billion per year. To date the majority of efficacy and safety testing in ophthalmological drug development is performed on animal models (rodents and rabbits), while these provide significant insight, they fall short of accurately modelling the complex structure of the human retina. With significant scientific advances in generation of in vitro human retinas by stem cell technology and industrial interest for vision restoration, STIMOS project aims to develop a system for simultaneous light stimulation of multiple retinal samples. STIMOS will be used in combination with MaxTwo, a multi-well high-resolution MEA platform for drug testing and sample functional studies, in order to test preclinical visual restoration techniques. STIMOS project enabled the grantee to transition from academic environment to industry. Within the STIMOS project, the grantee used his scientific and technical skills to develop a product prototype, which can be commercially exploited by MaxWell Biosystems.

Data: CORDIS, © European Union