PRISAR2 · proactive monitoring of cancer as an alternative to surgery

Lines connect the coordinator with its partners.

Project objective

From 2016 -2019, the “first” PRISAR consortium implemented the first Dutch RISE project of H2020 to investigate the use of imaging technologies and hybrid fluorescence/radionuclide probes for the surgical intervention of cancer. This PRISAR project provided a career-enabling human resource plethora of inter-disciplinary and inter-sectoral secondments, which resulted in the development, of not only a hybrid probe for image-guided surgery, but also a variety of tools and instruments. We now propose a new project, PRISAR2, to implement the next logical phase of this work, which is to clinically translate new and innovative monitoring technologies from industry. This will provide better patient selection and increase the surveillance window to allow for better treatment options over time and avoid surgery. This will involve developing new ‘watch and wait’ strategies to study the behaviour of the cancer so that any risks can be minimized. This would lead to a better clinical outcome and quality of life (QOL) for the patient and maximize the benefits of an active monitoring policy for both the patient and the healthcare system. When a patient is discovered to have cancer, one of the primary goals is to have the tumour removed by surgery. Here, however, we aim to (a) develop new monitoring technologies from industry so that the surveillance window can be increased to allow for better treatment options over time and to avoid surgery, (b) develop new ‘watch and wait’ strategies in order to study the behaviour of the cancer so that any risks to the patient can be minimised leading to a better clinical outcome and (c) train a new generation of preclinical and clinical scientists to be able to implement this new concept as standard of care and to maximise the benefits of an active monitoring policy.

Original text from CORDIS.

Participants

• PERCUROS BV · 's-Gravenhage (Den Haag)CoordinatorNetherlands
• ACADEMISCH ZIEKENHUIS LEIDEN · LeidenNetherlands
• ASSOCIAZIONE HAND IN HAND · NemiItaly
• ASSOCIAZIONE TOURISM · NEMIItaly
• CHIPDX IVS · VaerloseDenmark
• DATAR CANCER GENETICS (EUROPE) GMBH · EckersdorfGermany
• DES SOLUTIO - SOLUCOES E CONSULTORIA CIENTIFICA LDA · Charneca De CaparicaPortugal
• ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM · RotterdamNetherlands
• FUJIFILM SONOSITE BV · AmsterdamNetherlands
• HAMMERSMITH MEDICINES RESEARCH LTD · LondonUnited Kingdom
• HEINRICH-HEINE-UNIVERSITAET DUESSELDORF · DusseldorfGermany
• NEMI TERRITORIO E TURISMO · NemiItaly
• PROGREDUM GMBH · KaiserslauternGermany
• SERANOVO BV · LeidenNetherlands
• SURGIMAB SAS · MontpellierFrance
• TACIT BIO INNOVATION LIMITED · Sutton ColdfieldUnited Kingdom
• TECHNICKA UNIVERZITA VO ZVOLENE · ZVOLENSlovakia
• TECOBIOSCIENCES GMBH · LANDSHUTGermany
• THE UNIVERSITY OF EDINBURGH · EdinburghUnited Kingdom
• THE UNIVERSITY OF LIVERPOOL · LIVERPOOLUnited Kingdom
• THE UNIVERSITY OF SHEFFIELD · SHEFFIELDUnited Kingdom
• UNIVERSITA DEGLI STUDI DI CAMERINO · CamerinoItaly
• UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II · NapoliItaly
• UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS · GoettingenGermany
• UNIVERSITE DE STRASBOURG · StrasbourgFrance

Links

• View on CORDIS
• DOI: 10.3030/872860
• https://ec.europa.eu/research/participants/documents/downloadPublic?documentIds=080166e5f07a7812&appId=PPGMS
• https://ec.europa.eu/research/participants/documents/downloadPublic?documentIds=080166e5f4af885c&appId=PPGMS