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H2020Doctoral network2020–2025

RENOIR · REcreating the ideal Niche: environmental control Of cell Identity in Regenerating and diseased muscles

Horizon 2020 — Marie Skłodowska-Curie Actions

Duration
2020-05-01 → 2025-04-30
EU contribution
€3,482,325
Participants
14
Scheme
MSCA-ITN

Lines connect the coordinator with its partners.

Results in brief

REcreating the ideal Niche: environmental control Of cell Identity in Regenerating and diseased muscles

The project aims to address one of the major challenges in Europe that is to have an ageing population, which is healthy and active, and to improve the quality of life of people affected by chronic diseases. Skeletal and cardiac muscle ischemia are amongst the major causes of exacerbation of several diseases and morbidity in the population that represent an important social and economic burden for our society. In this context, the overall objective of RENOIR research program is to unravel, the decline in skeletal and cardiac muscle mass and function during ageing and disease, using advanced biotechnological tools. Specific scientific objectives of the project are to identify molecular signatures and interaction patterns of muscle niche components and to combine biomaterials and biopharma for improved ex vivo models and in vivo regeneration. The project innovations will provide a strong basis for the growth of the involved biotechnology company.

Data: CORDIS, © European Union

Project objective

RENOIR is a European Training Network that brings together 12 beneficiaries (10 academic and 2 industrial), and 3 partner organizations (a private Onlus Foundation, a pharmaceutical company, and a university) to train 13 Early Stage Researchers with an interdisciplinary profile for outstanding carriers as leaders in the field of muscle regeneration and aging. Receiving a training programme in both scientific and transferable skills and using unique expertise and tools at the frontier between biology and engineering, this new generation of versatile researchers will dissect the cellular and molecular mechanisms underlying impaired muscle composition and function, paving the way to new therapeutic interventions for muscle disease and aging. This will happen through collaborative and synergistic projects between academia and industry.

Original text from CORDIS.

Participants

  • UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA · MilanoCoordinatorItaly
  • CHERRY BIOTECH · MONTREUILFrance
  • CONSIGLIO NAZIONALE DELLE RICERCHE · RomaItaly
  • DEBRECENI EGYETEM · DebrecenHungary
  • EDEN TECH · ParisFrance
  • FONDAZIONE SANTA LUCIA · RomaItaly
  • HMGBIOTECH SRL · MilanoItaly
  • KING'S COLLEGE LONDON · LondonUnited Kingdom
  • TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD · HaifaIsrael
  • THE UNIVERSITY OF MANCHESTER · ManchesterUnited Kingdom
  • UNIVERSIDAD POMPEU FABRA · BarcelonaSpain
  • UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II · NapoliItaly
  • UNIVERSITE LYON 1 CLAUDE BERNARD · Villeurbanne CedexFrance
  • UNIVERSITE PARIS XII VAL DE MARNE · CreteilFrance

Links

Data: CORDIS, © European Union