H2020Individual fellowship2023–2024

DNA-BIO · Diamond based nanomaterials for biosensing applications

Horizon 2020 — Marie Skłodowska-Curie Actions

Duration
2023-01-01 → 2024-12-31
EU contribution
€204,848
Participants
2
Scheme
MSCA-IF

Lines connect the coordinator with its partners.

Results in brief

Diamond based nanomaterials for biosensing applications

Biosensors are analytical devices that encompass a sensitive biological detection material or a biological receptor capable of offering ultrasensitive detection of markers specific for diseases. Nanomaterials and nanostructures in particular diamond-based materials exhibit attractive properties for biosensing, but their fabrication presents with technical challenges. The evolution of next-generation, integrated, multi-functional sensing, monitoring, and non-destructive techniques calls for the integration of miniaturized sensors into microchips, such as microelectromechanical systems (MEMS). Recent progress in nanotechnology, along with innovative approaches to synthesizing nanomaterials and fabricating MEMS devices, has simplified the design and development of advanced sensing strategies and portable devices. The project developed novel diamond nanostructures that can be selectively functionalised on their surface to serve specific sensing applications including biological sensing and imaging. The outcome is the introduction of the next generation of high-resolution biosensors and/or electrochemical sensors to both the research community and the biomedical field. We have successfully demonstrated diamond MEMs sensors, with promising biomedical applications in the fields of atomic force microscopy probes, magnetic sensors, and mass sensors. We also demonstrated electrochemical sensors, which are promising tools for monitoring metabolic conditions such as gout related disorders. Its fast response and compatibility with wearable and portable health monitoring devices further highlight its potential applications in clinical diagnostics, biomedical research, and environmental sensing.

Data: CORDIS, © European Union

Project objective

This proposal is a 24-month Marie Curie Global Fellowship scheme which involves a British experienced researcher to undertake a training-through-research project on the development of cutting-edge diamond based nanomaterials for biosensing applications (DNA-BIO) in liaison with National Institutes for Materials Science (NIMS), Japan. Dr. Haitao Ye has been conducting original research into diamond growth and characterisation and device fabrication at University of Leicester (UoL), and has established an excellent track record. NIMS is a world-leading research institution in the field with an international reputation of technological innovation, enterprise participation, and knowledge transfer. The proposal will tackle the challenging development of multifunctional nanodiamond species and assess their applications to bioimaging and sensing. Success will deliver new approaches for both surface functionalisation and doping of nanodiamonds and bring high-resolution bioimaging sensors to the research community. It will contribute to the EU’s economy by developing next-generation biomedical sensor and significantly widening the competences of the fellow to reach his professional maturity with interdisciplinary expertise and complementary skills unique to the ERA. The fellow is leading the development of UoL’s teaching and research activities in surface engineering and biomaterials and the highest quality training under supervision of internationally leading scientists is indispensable for his career development which will in turn benefit the UK and the EU.

Original text from CORDIS.

Participants

  • UNIVERSITY OF LEICESTER · LeicesterCoordinatorUnited Kingdom
  • NATIONAL INSTITUTE FOR MATERIALS SCIENCE · TsukubaJapan

Links

Data: CORDIS, © European Union