STRIKE · Comprehensive STRategIes to tacKlE malignant tumors: from nanomedicine and theranostics to precision medicine
Horizon Europe — Marie Skłodowska-Curie Actions
- Duration
- 2023-01-01 → 2026-12-31
- EU contribution
- €2,106,835
- Participants
- 12
- Scheme
- HORIZON-TMA-MSCA-DN
Lines connect the coordinator with its partners.
Results in brief
Comprehensive STRategIes to tacKlE malignant tumors: from nanomedicine and theranostics to precision medicine
The European Union requires highly trained scientists in the fields of design, synthesis, characterization, biological evaluation, and regulation of innovative multifunctional materials to remain competitive in advanced nanomedicine technologies. The STRIKE project (101072462 — STRIKE — HORIZON-MSCA-2021-DN-01) aims to foster excellence in both applied cancer research and the training of doctoral candidates (DCs). STRIKE is built on two main pillars: a) Establishing a comprehensive, interdisciplinary, and intersectoral research network to train a new generation of entrepreneurial, ultidisciplinary early-stage researchers (ESRs), b) Leveraging recent advancements in nanotechnology and liquid biopsy to develop innovative imaging and therapeutic strategies for osteosarcoma (OS) and breast cancer (BC) diagnosis. The project started on January 1st , 2023, with a duration of 48 months and a maximum EU contribution of €2,106,835.20. The consortium consists of eight beneficiaries, coordinated by the University of Messina (IT). The STRIKE Kick-off Meeting, held in Taormina, Italy (January 27-28, 2023), marked a crucial milestone, establishing a strong scientific network and facilitating discussions on project objectives. This in-person meeting, one of the first post-pandemic, led to key achievements such as the signing of the Consortium Agreement, the launch of the STRIKE website, and the finalization of the recruitment strategy for eight DCs. To ensure broad visibility, STRIKE's recruitment campaign was extensively promoted via social media, academic platforms, Euraxess, and the project’s website (https://strike.unime.it). The call attracted 291 applications from 187 candidates, the most suitable candidates were invited for the interview and the final selections was completed by May 2023. In October 2023, all 8 DCs met online for the first time the STRIKE network, fostering connections and establishing communication and dissemination strategies for the project's website and social media platforms. The first STRIKE scientific meeting took place on January 24-26, 2024, in Bologna, Italy. This event gathered DCs, board members, consortium members, and distinguished scientists. The project coordinator provided a comprehensive overview of the main objectives and strategic direction of the initiative. Additionally, each DC, alongside with their primary supervisor, delivered an introductory presentation covering their institution, academic background, research objectives, and initial project actions. A training session on “European Public Funding Schemes for R&D and Innovation and Technology Transfer “European Public Funding Schemes for R&D and Innovation” was delivered by the associated partner STEM Innovation. The training provided ESRs with essential skills and insights into navigating the complexities of research funding and innovation. Through theoretical lessons and proposal drafting exercises, they received valuable feedback from both instructors and peers, enhancing their understanding of effective proposal development and funding opportunities The Second STRIKE Scientific & Progress Meeting took place on June 11-12, 2024, at Nantes University, France. This event provided a platform for DCs to present their initial research findings, exchange ideas, and plan future research activities. Additionally, expert researchers in cancer, microfluidics, and osteosarcoma delivered insightful presentations that enriched discussions and guided the next phase of the project. The meeting concluded on a high note, reinforcing the commitment to continued collaboration. In the following months, the DCs and their supervisors have maintained ongoing communication and monitoring to ensure the successful execution of experiments, protocols, and objectives in alignment with the project proposal.
Data: CORDIS, © European Union
Project objective
STRIKE-DN will raise excellence in research and training in nanomedicine/precision medicine creating new generation of entrepreneurial and innovative multidisciplinary doctoral candidates. New experimental aspects on design and synthesis of nanostructured magnetic materials will be applied to the development of innovative magnetic field-responsive nanotherapeutics for osteosarcoma (OS) combinational therapy. Moreover, the peculiar features of STRIKE nanomaterials will be exploited for liquid biopsy using biological samples of BRCA+ breast cancer (BC) patients. The cooperation among outstanding universities, research institutes and industries will provide the DCs with trans-national exchanges and the most innovative research trainings in novel anticancer therapeutic strategies, including in vivo biological evaluation, imaging in OS and early diagnosis in BC. STRIKE will provide enhanced career perspectives in academic and non-academic sectors for 8 DCs in highly innovative fields by interdisciplinary mobility among 12 institutes/companies in 8 EU countries. STRIKE aims to: 1) develop 8 highly skilled employable doctoral candidates; 2) enhance interdisciplinary capacity and cooperation within the EU nanomedicine and precision medicine research networks; 3) strengthen EU’s competitiveness and growth in nanomedicine and precision medicine through the translation of the consortium research/innovation outputs. The consortium will fulfill its goals through: a) achieving research excellence; b) providing a complete cutting edge research and innovation training program with some of the European top research institutes and industry partners; c) hosting interdisciplinary and commercial workshops, seminars and outreach events; d) maximizing knowledge transfer using Open Science and patents; e) delivering highly trained professionals, whose profiles fit within the requirements of academia, industry and public/private institutions, fostering their employability and promoting the innovation of EU research.
Original text from CORDIS.
Participants
- UNIVERSITA DEGLI STUDI DI MESSINA · MessinaCoordinatorItaly
- CONSIGLIO NAZIONALE DELLE RICERCHE · RomaItaly
- CONSORTIUM FOR GENOMIC TECHNOLOGIESSOCIETA BENEFIT SRL · MilanItaly
- CYCLOLAB CIKLODEXTRIN KUTATO-FEJLESZTO KFT · BudapestHungary
- MEDIZINISCHE UNIVERSITAET WIEN · WienAustria
- NANOTECH SOLUTIONS SOCIEDAD LIMITADA · VillacastinSpain
- NANTES UNIVERSITE · NantesFrance
- NATIONAL UNIVERSITY OF IRELAND MAYNOOTH · MaynoothIreland
- STEM INNOVATION srl · RomaItaly
- UNIVERSIDAD AUTONOMA DE MADRID · MadridSpain
- UNIVERZITA PALACKEHO V OLOMOUCI · OlomoucCzechia
- WILEY-VCH VERLAG GMBH & CO KGAA · WeinheimGermany
Links
- View on CORDIS
- DOI: 10.3030/101072462
- https://ec.europa.eu/research/participants/documents/downloadPublic?documentIds=080166e507d9aae3&appId=PPGMS
- https://ec.europa.eu/research/participants/documents/downloadPublic?documentIds=080166e507d9c0d0&appId=PPGMS
- https://ec.europa.eu/research/participants/documents/downloadPublic?documentIds=080166e5f866ef03&appId=PPGMS
- https://ec.europa.eu/research/participants/documents/downloadPublic?documentIds=080166e5fc7ab3cd&appId=PPGMS
- https://ec.europa.eu/research/participants/documents/downloadPublic?documentIds=080166e5fde88bda&appId=PPGMS
- https://ec.europa.eu/research/participants/documents/downloadPublic?documentIds=080166e5fde88bdd&appId=PPGMS
Data: CORDIS, © European Union
