WallSATisFaction · The impact of SA signaling in CWI impairment and downstream factors
Horizon Europe — Marie Skłodowska-Curie Actions
- Duration
- 2023-04-01 → 2025-09-30
- EU contribution
- €210,911
- Participants
- 1
- Scheme
- HORIZON-TMA-MSCA-PF-EF
Lines connect the coordinator with its partners.
Results in brief
The impact of SA signaling in CWI impairment and downstream factors
Plant survival and productivity depend on their ability to sense and adapt to constantly changing environmental conditions. Drought, osmotic stress, and mechanical strain threaten plant growth daily. They use a complex signaling networks to monitor the challenges and initiate adaptive responses to ensure their survival. Among the networks, cell-wall integrity (CWI) maintenance mechanism is fundamentally important because it ensure functional integrity of the cell wall during exposure to stress. If the cell wall is weakened or stressed, receptor-like kinases (RLKs) detect the weakness and trigger adaptive modification sin cellular and cell wall metabolism to restore integrity and strengthen resilience. The WallSATisFaction project addressed a key knowledge gap by studying how the receptor-like kinase THESEUS1 (THE1) mediates CWI signaling and how this pathway regulates salicylic acid (SA) induction, transcriptional reprogramming, and primary cell-wall metabolism. The project pursued three main scientific objectives: - Identify signal transduction elements involved in SA induction upon CWI impairment. - Discover novel transcriptional regulators of primary wall metabolism and stress adaptation. - Characterize the molecular mode of action of these regulators and their target networks. This research directly supports European and global sustainability goals. CWI signalling enables plants to adapt to environmental stress, which influences crop performance. This determines in turn agricultural productivity, resource efficiency, and ecological stability. The project therefore contributes to the European Green Deal, the Farm-to-Fork Strategy, and the EU Biodiversity Strategy for 2030, all of which prioritize sustainable agriculture, food security, and resilience to climate change.
Data: CORDIS, © European Union
Project objective
The plant cell wall (CW) is a crucial defense layer surrounding plants cells. CW composition and structure are directly associated with environmental stresses and biomass production. Cell Wall Integrity (CWI) maintenance is a crucial key player responsible for monitoring and maintaining plant CW composition and structure under biotic and abiotic stresses. Thus, the new knowledge and understanding of the CWI machinery have enormous potential to increase crop production and develop new highly adaptive crop species. The CWI maintenance mechanism involves receptor-like kinases and ion channels in the plasma membrane, which perceive signals arising from CWI impairment and modulate downstream signaling cascades, leading to changes in cytoskeleton organization, phytohormone production (ABA, SA, JA, and ethylene), gene expression, and cell wall composition/structure. I will use my expertise in signaling transduction pathways and combine them with the knowledge and skill used host lab on CWI signaling pathways to determine the mechanism regulating SA responses and downstream factors of plant cells in CWI impairments. Therefore, my project aims to discover transcriptional regulators mediating the response to impairment of primary cell wall integrity and characterize signal transduction elements controlling SA induction and modulating SA-controlled responses. I will share the results with the scientific community and the public using social networks, attending international conferences, and publish research outcomes in a high-impact scientific journal in an open-access format. This project will form the foundation of my future career as a researcher, and the project results can be used to increase crop production and develop new highly adaptive crop species.
Original text from CORDIS.
Participants
- NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU · TrondheimCoordinatorNorway
Links
- View on CORDIS
- DOI: 10.3030/101066093
- https://ec.europa.eu/research/participants/documents/downloadPublic?documentIds=080166e511262f7c&appId=PPGMS
- https://ec.europa.eu/research/participants/documents/downloadPublic?documentIds=080166e524e7966c&appId=PPGMS
Data: CORDIS, © European Union