X-MiND · Next generation X-ray/H+ Micro and Nano Scintillating Detectors
Horizon Europe — Marie Skłodowska-Curie Actions
- Duration
- 2022-11-01 → 2026-06-30
- EU contribution
- €300,442
- Participants
- 4
- Scheme
- HORIZON-TMA-MSCA-PF-GF
Lines connect the coordinator with its partners.
Results in brief
Next generation X-ray/H+ Micro and Nano Scintillating Detectors
Soft and hard X-ray technologies are now widely used in the field of medical physics (radiation therapy), 3-D object imaging (healthcare and forensic), and in-depth material probing (microscopy), etc. Particularly, in clinical medicine, hard X-rays and charged particles are mostly used for radiation therapy and imaging to treat cancer, spot tumors, and damage malignant tumors. In this sense, the modern radiation therapy treatment is driven by the ongoing demand for suitable dosimeters for accurate dose measurement in various radiation beams (photon, proton, electron, ion, etc.). In recent times, dosimetry at small fields has emerged to deliver precise and highly controlled doses at the right location in the human body for destroying cancerous cells while sparing surrounding healthy tissues. However, the industrially developed dosimeters/detectors are ill-suited for small fields due to significant size requirements, volume averaging effect, lack of sensitivity and spatial resolution, low signal-to-noise ratio, significant corrections, Cerenkov effect, etc. Thus, quality treatment is still hampered and continues to risk the patients. Till now, no detector has been introduced to address these issues and for versatile use. In addition, scintillator-based imaging systems still suffer from low compactness, modest response time, and low spatial resolution, which present strong limitations in the existing technology. In this context, this research project aims to design and develop a novel, small-scale, real-time, and highly sensitive X-ray/H+ Micro/Nano Scintillating Detector (X-MiND). The detectors are planned to be tested for high-energy photon and particle beam characterizations, small-field dosimetry, and high sensitivity. Subsequently, a nanometric scintillating detector is planned to be demonstrated in surface physics applications, targeting high-resolution imaging. Therefore, the medical outcomes of this research will explore miniaturized dosimetry and precise dose verification in the small fields. The physics outcomes are expected to be applied in direct surface imaging. The new fundamental knowledge developed in this project could be applied to multiple domains.
Data: CORDIS, © European Union
Project objective
Modern radiation therapy treatment is driven by the everlasting demand for suitable detectors that can perform under different radiation beams (photon, proton, electron, ion, etc.) at small fields. The industrially developed dosimeter/detectors are still limited by the significant size requirement, volume averaging effect, lack of sensitivity, correction factors, and low signal-to-noise ratio, etc. Thus, quality treatment is still hampered and continues to risk the patients. In addition, scintillator-based X-ray cameras are still suffered from low compactness, modest response time, and crosstalk, which shows strong limitations in the existing technology. In this context, this research work is devoted to the design and fabrication of a novel extremely compact, real-time, dynamic, and highly sensitive X-ray/H+ Micro/Nano Scintillating Detector (X-MiND). The developed micro-detector will be tested for high-energy photon and particle beam characterizations along with simulation techniques. A multi-dosimeter system exploited from a bundle of single detectors will be realized and tested, targeting the next generation X-ray cameras. Subsequently, a nanometric scintillating detector will be demonstrated in surface physics application in synchrotron targeting high-resolution local 2D chemical mapping of a material by employing a novel dual-probe technique. Thus, the medical outcomes of this research will explore miniaturized dosimetry, exact dose verification in the small field that initiates early-stage tumor treatments and the first step of new generation X-ray cameras with improved performances. The physics outcomes are expected in the direct surface imaging of X-ray free-standing waves (XSW). The new fundamental knowledge developed in this project could be applied to other multiple domains. From the project, I aim to improve my expertise by training-through-research with leading experts worldwide and bring this knowledge back to Europe to share and integrate me.
Original text from CORDIS.
Participants
- UNIVERSITE D'AIX MARSEILLE · MarseilleCoordinatorFrance
- CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS · ParisFrance
- PAUL SCHERRER INSTITUT · VILLIGEN PSISwitzerland
- UCHICAGO ARGONNE LLC · Chicago IlUnited States
Links
- View on CORDIS
- DOI: 10.3030/101062690
- https://ec.europa.eu/research/participants/documents/downloadPublic?documentIds=080166e50b0dda16&appId=PPGMS
Data: CORDIS, © European Union
