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HEDoctoral network2023–2027

ETERNITY · FuEl ThE bRaiN In healtThY aging and agE-relateD diseases

Horizon Europe — Marie Skłodowska-Curie Actions

Duration
2023-02-01 → 2027-01-31
EU contribution
€2,629,260
Participants
14
Scheme
HORIZON-TMA-MSCA-DN

Lines connect the coordinator with its partners.

Results in brief

FuEl ThE bRaiN In healtThY aging and agE-relateD diseases

The global population is ageing, placing increasing pressure on healthcare systems to manage age-related diseases. In Europe, there is a critical need for innovation, expertise, and knowledge to drive advancements in preventing and treating metabolic alterations in the ageing brain. Ensuring brain health throughout life and ageing remains a major priority. The FuEl ThE bRaiN In healtThY aging and age-related diseases (ETERNITY) project is actively addressing this challenge. With an ambitious goal of understanding how brain metabolic pathways respond to physiological and pathological stimuli, ETERNITY is working to identify new metabolic targets as a foundation for future personalized therapies. Tackling these complex issues requires strong collaboration between academia and industry, and ETERNITY is fostering precisely this environment. Through its interdisciplinary and intersectoral approach, the project is already generating valuable insights into the mechanisms underlying impaired brain metabolism. By leveraging the complementary expertise of its partners, ETERNITY will also identify novel pharmaceutical targets and developing potential nutritional interventions. Beyond research, the project is strengthening European innovation capacity by training a new generation of researchers who are gaining firsthand experience in academia, the pharmaceutical sector, and the food supplement industry. Doctoral Candidates (DCs) within ETERNITY are being equipped with cutting-edge methodological skills, innovation-driven thinking, and transferable competencies essential for impactful careers in both research and industry. As the project progresses, its collaborative efforts and training initiatives will contribute to one of the greatest societal challenges of our time: promoting brain health during ageing and delaying the onset of neurodegenerative diseases.

Data: CORDIS, © European Union

Project objective

The worldwide population is ageing and putting our healthcare systems under pressure to cope with age-related diseases. In Europe, there is a need for innovation, knowledge and experts who can prompt significant changes to improve prevention and innovative interventional strategies to counteract altered metabolism in brain during ageing and related disorders. The priority is to ensure brain health throughout life and during ageing. Increased collaboration between academia and private sector is the required milieu to overcome this challenge.The “FuEl ThE bRaiN In healtThY aging and agE-relateD diseases” ETERNITY will contribute to the strengthening of the European innovation capacity by training a new generation of researchers with experience and full understanding of the requirements of academia, pharmaceutical and food supplement companies, and the society.ETERNITY research programme will focus on brain metabolism as a highly promising yet under-explored area. Given the complementary expertise, ETERNITY will have excellent opportunities to delineate different pathways underlying impaired brain metabolism to identify novel pharmaceutical targets and/or nutritional interventional strategies to counteract ageing and related disorders.The early-stage researchers (DCs) will be trained in this environment and provided with a mind-set of future commercial and clinical utilization of their research findings. Apart from the innovative and collaborative approach of the research programme, the DCs will also be provided with a training programme where cutting-edge methodology, innovation and transferable skills are key components.The trained DCs will have excellent intersectoral and interdisciplinary career opportunities and will, together with the ETERNITY partners, provide a solid ground to tackle one of the major societal challenges of our century: finding therapies to promote brain healthy ageing and delay the onset of neurodegenerative diseases.

Original text from CORDIS.

Participants

  • UNIVERSITA DEGLI STUDI DI MILANO · MilanoCoordinatorItaly
  • AVENCELL EUROPE GMBH · DresdenGermany
  • CF CONSULTING FINANZIAMENTI UNIONE EUROPEA SRL · MilanoItaly
  • CHARITE - UNIVERSITAETSMEDIZIN BERLIN · BerlinGermany
  • DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV · BonnGermany
  • Gesellschaft zur Förderung der Lebenswissenschaften Heidelberg GmbH · HeidelbergGermany
  • INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE · ParisFrance
  • ORION OYJ · EspooFinland
  • Sofinol SA · MannoSwitzerland
  • THE EUROPEAN BRAIN COUNCIL AISBL · Bruxelles / BrusselBelgium
  • The Visual Agency srl · MilanoItaly
  • UNIVERSIDAD DE SALAMANCA · SalamancaSpain
  • UNIVERSITATSKLINIKUM BONN · BonnGermany
  • UNIVERSITE DE BORDEAUX · BordeauxFrance

Links

Data: CORDIS, © European Union