RECIRCULATE · The development of bio-supported homogeneous organocatalysts with improved recycling potential through sequential de- and re-polymerization and their use in CO2 valorization catalysis
Horizon Europe — Marie Skłodowska-Curie Actions
- Duration
- 2023-06-19 → 2025-06-18
- EU contribution
- €181,153
- Participants
- 2
- Scheme
- HORIZON-TMA-MSCA-PF-EF
Lines connect the coordinator with its partners.
Results in brief
The development of bio-supported homogeneous organocatalysts with improved recycling potential through sequential de- and re-polymerization and their use in CO2 valorization catalysis
This work presents the development of new biodegradable plastics that can carry and release drug molecules in a controlled way. Researchers created two types of specialized building blocks (cyclic carbonates) that were chemically linked to a drug called oxaprozin. These were then used to make a new kind of polymer that can be precisely tuned for drug content. Importantly, the material can break down under specific conditions to release the active drug and recover useful by-products, showing promise for applications in controlled drug delivery and recyclable medical materials.
Data: CORDIS, © European Union
Project objective
The use of homogeneous catalysis is currently limited as they lack the ability to be easily recycled, and thermal deactivation of the catalyst cannot be always avoided. These features present important hurdles for the application of homogeneous catalysts in commercial processes and represents an open challenging. Designing ways to bridge the advantages properties of homogeneous and heterogeneous catalysis through the creation of supported homogeneous catalysts with well-defined active sites having high stability and recycling potential creates new incentives for circular type homogeneous catalysts with application potential in synthetic chemistry. In this project, several approaches are presented to realize this challenging goal. First, well-known N-heterocyclic bases such as TBD and DBU will be immobilized onto a biobased polycarbonate and their activity optimized in the synthesis of glycidol carbonate by a sequential catalyst testing-depolymerization-repolymerization approach. The depolymerization will be facilitated by a base catalyst, while the repolymerization will be carried out through a known procedure developed at the host laboratory. This allows to optimize and fine-tune the catalyst structure in terms of active site separation, concentration and local micro-environment. In order to be able to extend the recycling of the catalyst components to a fully recyclable system, a cross-linked version will be created and tested during an industrial secondment. A second strategy builds on a controlled copolymerization of pre-functionalized biobased monomers that feature two separate catalyst components. Their successful copolymerization and variation of their relative ratio permits the optimization of the catalytic activity of this binary system in CO2 valorization through a similar catalyst testing-depolymerization-repolymerization sequence, and ultimately to a generic process that allows to recycle a homogeneous catalyst through a unique approach.
Original text from CORDIS.
Participants
Links
- View on CORDIS
- DOI: 10.3030/101110356
- https://ec.europa.eu/research/participants/documents/downloadPublic?documentIds=080166e505ffab56&appId=PPGMS
- https://ec.europa.eu/research/participants/documents/downloadPublic?documentIds=080166e51cbada58&appId=PPGMS
Data: CORDIS, © European Union