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HEDoctoral network2023–2027

INSIDE-HEART · multI-discipliNary, multi-Sectoral and multi-national trainIng network on Digital biomarkErs for supraventricular arrHythmia charactErizAtion and Risk assessmenT

Horizon Europe — Marie Skłodowska-Curie Actions

Duration
2023-11-01 → 2027-10-31
EU contribution
€2,667,694
Participants
15
Scheme
HORIZON-TMA-MSCA-DN

Lines connect the coordinator with its partners.

Results in brief

multI-discipliNary, multi-Sectoral and multi-national trainIng network on Digital biomarkErs for supraventricular arrHythmia charactErizAtion and Risk assessmenT

According to the World Health Organization, cardiovascular diseases are the leading cause of death accounting for 30% of deaths worldwide. Among these diseases, the incidence and prevalence of pathologies related to atrial electrical disfunctions, mainly involving supraventricular arrhythmias (SVAs) such as atrial fibrillation (AF), atrial flutter (AFL), supraventricular tachycardia (SVT), are today reaching pandemic proportions. The overarching goal of INSIDE-HEART is to demonstrate that digital biomarkers derived from data collected by innovative sensing techniques, such as wearable sensors, non-dedicated devices and sensor networks, can be reliably quantified to track the risk of SVAs. The consortium includes 6 academic, 3 industrial and 1 clinical Beneficiaries and 1 clinical and 2 industrial Partners to provide scientific support, secondments and training. In this scenario, INSIDE-HEART will address the challenging problems related to collection, processing and relevance of digital biomarkers in the field of SVAs. This aim will be reached by training a new profile of modern professional researcher with multidisciplinary competencies, including in Responsible Research and Innovation (RRI) principles and in Open Science (OS) practices, who can transfer advances in basic science to market and health care system. From a scientific point of view, the specific scientific objectives of INSIDE-HEART are: 1. Diagnosis and prognosis of SVAs through digital biomarkers 2. Risk assessment of life-threatening events in patients with SVAs

Data: CORDIS, © European Union

Project objective

INSIDE-HEART brings together universities, companies and hospitals from countries (Italy, Finland, France, Israel, Netherlands, Spain, and Sweden) with the main scope of establishing a multi-disciplinary network to tackle the design and the early-phase validation of digital biomarkers, specifically targeting the diagnosis of supraventricular arrhythmias (SVAs) and their associated potential for adverse risk assessment, via the joint combination of signal processing, artificial intelligence and non-clinical devices. This will be achieved by performing excellent research through a unique doctoral training “without walls” among field-expert academic, industrial and clinical entities. The composite nature of the INSIDE-HEART network ensures a highly qualified training and research infrastructure for the specific goal, which aims to generate a new profile of researcher with multi-sectoral expertise able to fill the existing gap, i.e., the absence of digital biomarkers for SVAs reliably estimated with non-clinical devices, taking into account basic research, clinical needs and business interests. Research and training are designed to consider relevant aspects such as public concern of private data management, gender and ethics related to SVAs, all according to Responsible Research & Innovation principles and Open Science practices.All activities in INSIDE-HEART are designed to pursue innovation in three domains: i) Educational domain – by implementing a new multi-sectoral paradigm of PhD training to shape modern professional researchers with cross-competencies in the field, and able to accelerate the translation from basic science to market and clinics; ii) Basic science domain - by producing new knowledge about digital biomarkers by means of a multi-sectoral approach to explore the complex aspects related to SVAs; and iii) Technological domain – by developing new data-driven and model-based methodologies to compute digital biomarkers and support the clinical decision.

Original text from CORDIS.

Participants

  • POLITECNICO DI MILANO · MilanoCoordinatorItaly
  • CARDIO CALM SRL · MONTICHIARIItaly
  • CENTRO CARDIOLOGICO MONZINO · MilanoItaly
  • EMPATICA SRL · MILANOItaly
  • FUNDACION INSTITUTO DE INVESTIGACION SANITARIA ARAGON · ZaragozaSpain
  • LUNDS UNIVERSITET · LundSweden
  • MEDTRONIC BAKKEN RESEARCH CENTER B.V. · MaastrichtNetherlands
  • PRECORDIOR OY · TURKUFinland
  • RDS · StrasbourgFrance
  • SMART SOLUTIONS TECHNOLOGIES SL · PATERNA VALENCIASpain
  • TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY · HaifaIsrael
  • TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD · HaifaIsrael
  • TURUN YLIOPISTO · TurkuFinland
  • UNIVERSIDAD DE ZARAGOZA · ZaragozaSpain
  • UNIVERSITA DEGLI STUDI DI MILANO · MilanoItaly

Links

Data: CORDIS, © European Union