HEDoctoral network2024–2028

MiCCrobioTAckle · Advancing Research at the Intersection Between Gut Microbiota and Cancer Cachexia to Train Europe’s Future Leaders in Microbiota Medicine

Horizon Europe — Marie Skłodowska-Curie Actions

Duration
2024-11-01 → 2028-10-31
EU contribution
€3,237,962
Participants
28
Scheme
HORIZON-TMA-MSCA-DN

Lines connect the coordinator with its partners. CORDIS does not always give exact coordinates for projects before 2014. These points are placed at city or country level.

Project objective

Microbiota medicine is the new frontier in human health. The human gastrointestinal tract is home to trillions of microbes. Under normal conditions, these microbial communities drive physiological and homeostatic functions in the host; when altered, they can lead to severe disorders. With an increasingly recognized role in health and disease, the gut microbiota offers promising therapeutic and diagnostic potential to tackle various pathologies (incl. metabolic, neurological, and cardiovascular disorders). Its full clinical potential remains largely unrealized though, mostly due to the lack of critical mass capable of integrating the multiple scientific and translational dimensions of microbiota medicine. Grounded on a team of 180leading researchers and entrepreneurs from across 12 countries and dispersed disciplines (biological big data analytics, systems and synthetic biology, experimental and translational medicine), MiCCrobioTAckle will train 12 Doctoral Candidates (DCs) with the much-needed cross-disciplinary and -sectoral expertise to advance microbiota medicine. As course-setting disease, the DCs will focus on cancer cachexia (CC). CC is an excellent model to study the host-microbiota axis in the context of metabolic diseases and represents the paradigm of a devastating condition in urgent need of new and more efficient means of clinical management. Along MiCCrobioTAckle, the 12 high-calibre DCs will foster new discoveries with impact on CC, while driving scientific and technological progress in microbiota medicine in its broadest scope. By training the next generation of researchers with out-of-the-box thinking and an entrepreneurial mindset in microbiota medicine, MiCCrobioTAckle will safeguard the EU leadership in this vanguard and imperative biotech/pharma segment, while paving the way for the development of novel gut microbiota insights and tools to tackle multiple diseases with foreseeable impact on the well-being of billions of citizens worldwide.

Original text from CORDIS.

Participants

  • LEIBNIZ-INSTITUT FUR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE EV HANS-KNOLL-INSTITUT · JENACoordinatorGermany
  • ABZU APS · NordhavnDenmark
  • BIOFACTION KG · WienAustria
  • BIOMARKER TECHNOLOGIES (BMK) GMBH · MUNSTERGermany
  • CAELUS PHARMACEUTICALS B.V. · ZEGVELDCity levelNetherlands
  • CHR. HANSEN AS · HORSHOLMDenmark
  • Community Initiatives · OaklandUnited States
  • DANMARKS TEKNISKE UNIVERSITET · Kongens LyngbyDenmark
  • DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG · HeidelbergGermany
  • DNASense ApS · Aalborg ØstDenmark
  • FONDAZIONE CASA SOLLIEVO DELLA SOFFERENZA · San Giovanni Rotondo FgItaly
  • FRIEDRICH-SCHILLER-UNIVERSITÄT JENA · JENAGermany
  • HUN-REN SZEGEDI BIOLOGIAI KUTATOKOZPONT · SzegedHungary
  • HUN-REN Szegedi Biologiai Kutatokozpont · SzegedHungary
  • MS-OMICS APS · VEDAEKDenmark
  • OSLO CANCER CLUSTER SA · OsloNorway
  • Presymptom Health Ltd · LeedsUnited Kingdom
  • REFORMATUS PULMONOLOGIAI CENTRUM · TOROKBALINTHungary
  • RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG · HeidelbergGermany
  • SEMMELWEIS EGYETEM · BudapestHungary
  • SINGLE-CELL TECHNOLOGIES KFT · SzegedHungary
  • SNIPR BIOME APS · COPENHAGEN ODenmark
  • STICHTING AMSTERDAM UMC · AmsterdamNetherlands
  • SeqBiome Ltd. · BandonIreland
  • UNIVERSITAT ROVIRA I VIRGILI · TarragonaSpain
  • UNIVERSITE CATHOLIQUE DE LOUVAIN · LOUVAIN LA NEUVEBelgium
  • UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK · CorkIreland
  • UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN · DublinIreland

Links

Data: CORDIS, © European Union