Regulation of antioxidant and cell cycle genes in response to oxidative stress in plants
FP4 — Training and Mobility of Researchers
- Duration
- 1996-09-16 → 1998-09-15
- EU contribution
- —
- Participants
- 2
- Scheme
- RGI
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Project objective
Environmental stresses have been shown to induce strongly and transiently metabolism changes in plant cells such as ion fluxes and a so called oxidative burst. Hydrogen peroxide (H202), the major molecule produced by the oxidative burst was shown to play a dual role in both the induction of antioxidant genes and in the programmed cell death. This H202-induced-programmed cell death suggests that H2r2 may also involved in down-regulating genes responsible for the cell-cycle progression. Using a synchronisable tobacco cell suspension, the present project aims to answer the following questions: (1) does H202triggers a common signal transduction pathway responsible for the induction of antioxidant genes and the inhibition of cell cycle progression genes ? (2) what are the key steps of this pathway and is it possible to modify them through transgenic approch ? (3) what are the molecular mecanisms involved in the regulation of transcription of the both types of genes ?
Original text from CORDIS.
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Data: CORDIS, © European Union