Application of high cell density bioreactors to whey bioutilization - modelling and scale-up strategy

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Project objective

The objective of this project is the optimisation of the continuous fermentation of the deproteinized cheese whey in an airlift bioreactor (CALR) using a flocculating yeast strain at lab and pilot plant scale and the development of a suitable scale-up procedure for industrial application of fermentation.The project consists of five work packages:1. Fundamental investigation of the hydrodynamics and characterisation of all phases present in three- phase airlift bioreactor;2. Development of a three-phase hydrodynamic model enabling the reliable prediction of the main hydrodynamic parameters in batch and continuous airlift bioreactors during the fermentation process;3. Experimental verification of the hydrodynamic model on alcoholic fermentation of cheese whey permeate at lab-scale continuous airift biorector;4. Development of a complete bioreactor model and proposal of a suitable scale-up strategy for the airlift bioreactor;5. Implementation of whey fermentation at pilot plant-scale CALR. Verification of the scale-up strategy by means of a scale-down procedure.

Original text from CORDIS.

Participants

• UNIVERSIDADE DO MINHO · BRAGACoordinatorPortugal

Links

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