DNP4NANOCARAC · Dynamic nuclear polarization - enhanced high resolution solid-state NMR spectroscopy for atomic 3D structure determination of functionalized nanotubes and other nano-sized objects
FP7 — People (Marie Curie Actions)
- Duration
- 2009-04-01 → 2011-03-31
- EU contribution
- €176,804
- Participants
- 1
- Scheme
- MC-IEF
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Results in brief
Final Report Summary - DNP4NANOCARAC (Dynamic nuclear polarization - enhanced high resolution solid-state NMR spectroscopy for atomic 3D structure determination of functionalized nanotubes and other n
The intra-European fellowships (IEF) funding has enabled Dr Gaël De Paëpe to start his research activities at Indian and Northern affairs Canada (INAC) (Centre dEtudes atomiques (CEA) Grenoble). The two last years has been devoted to the installation of a very novel equipment at INAC: high field dynamic nuclear polarization (DNP) experiments. The experiment is currently being installed at micro and nanotechnology innovation campus (Minatec) and very encouraging preliminary results have been obtained. The other aspect of the IEF was to develop a low temperature nuclear magnetic resonance (NMR) probe. We are currently testing magic angle spinning under cryogneic conditions and five patent deposits are currently in progress. Besides the DNP and instrumentation development, we have also contributed to the development of new methods in solid-state NMR (one publication in journal of chemical physics and one paper pending for submission). Research activities: Axis one: DNP experiment setup - Initiate call for bids for a high field DNP experiment (magnet and gyrotron) - June-September 2010 - Active participation to laboratory setup in Minatec (moving scheduled in June 2011) - Biradical synthesis for DNP-- (Coll. SCIB) - Theoretical development for DNP experiments Axis two: Instrumentation for cryogenic NMR - (Coll. SBT/SCIB) - Test cryostat assembling for cryogenic NMR - preliminary test April 2011 - Patent deposit for new instrumentation in NMR -- in progress - Conception and preliminary test of a room temperature NMR probe Axis three: method development in solid-state NMR - Extension of the third spin assisted recoupling principles aiming at improving structure determination by solid state NMR. - Grant of a young researcher price to M. Giffard (PhD in the group) European magnetic resonance (Euromar) (Florence, July 2010) - Setting up of a collaboration aiming at studying by nanoparticles be DNP enhanced solid state NMR -- in progress
Data: CORDIS, © European Union
Project objective
This project aims at developing the instrumentation and methodology required to perform solid-state sub-nanometer scale structural studies by Nuclear Magnetic Resonance (NMR). In the last decades NMR has proven to be a priceless tool to probe structure and dynamics of systems as diverse as glasses, metal surfaces, polymers and proteins, etc. However, the low sensitivity of the technique currently limits its outreach in material science, chemistry and biology. In order to overcome this limitation, we plan to use a technique called Dynamic Nuclear polarization (DNP) which is able to hyperpolarize nuclear spins. The DNP phenomenon, discovered at low magnetic fields (< 0.3 T), is far from being new but its usage at high magnetic fields (5 to 20 T and more) constitutes an exciting ongoing challenge. Compared to traditional NMR where the signal originates from thermal polarization, DNP enables us to enhance the NMR signal to noise by 1 to 4 orders of magnitude (depending on the nuclei) by transferring the magnetization of unpaired electron spins (polarizing agents) to the surrounding nuclear spins. Utilizing emerging high frequency microwave technologies, optimized polarizing agents together with state of the high resolution solid-state NMR instrumentation and methods, we plan to develop original magnetic resonance experiments at high magnetic fields. This technique should allow bringing down the NMR detection threshold to micro/nano-molar concentration, studying larger molecular systems and performing multidimensional experiments orders of magnitude faster. The project will lead to numerous interdisciplinary applications to illustrate the potential of DNP-enhanced NMR to characterize new materials for the nanotechnologies (functionalized nanotubes, molecular wires, etc.), new polymers for energy (CNT embedded in polymers, etc.), and to determine the 3D atomic solid-state structure of biomolecules (membrane proteins, paramagnetic proteins, etc.).
Original text from CORDIS.
Participants
- COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES · ParisCoordinatorFrance
Links
Data: CORDIS, © European Union