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Mechanobiology explores how physical forces affect cellular processes, providing insights into areas like embryogenesis and tumor growth. Cells exert forces onto their environment; the tissue in which they live.

Malaria remains one of the world’s most persistent infectious diseases, causing hundreds of thousands of deaths every year and placing nearly half of the global population at risk. Although the disease is most common in sub-Saharan Africa,…

A breakthrough in precision diagnostics and treatement for breast cancer Breast cancer diagnosis and treatment face persistent challenges, with current methods often lacking the precision and ease of use required for optimal patient care. E…

Data4Healthcare is a novel postdoctoral programme hosted at the University of Oulu, Finland. The programme was established to train 25 postdoctoral researchers who can work with advanced data technologies, such as big data analytics, machin…

We are proposing a 4-year program of knowledge transfer and networking between academic institutions [University of Leicester (UK), University of Valencia (Spain), International Iberian Nanotechnology Lab (Portugal), University of Bologna (…

Disorders of consciousness (DOC) remain one of the most challenging conditions to assess and diagnose in modern clinical practice. Despite major advances in neuroscience, many patients emerging from coma continue to be misdiagnosed due to t…

The global consumption of metals and metalloids is increasing rapidly owing to an ever-growing demand from technology and renewable energy industries. Most of these metal(loid)s are defined as critical elements, since their supply is expect…

The general goal of the HydroTheC project is the development of a new non-toxic, natural, biocompatible, biodegradable, thermo-responsive, and injectable multidrug-loaded HG as an in situ depot system for the sustained intraperitoneal relea…

Myelin is an essential biological structure that allows the nervous system to transmit information rapidly and efficiently. It is produced by specialised glial cells called oligodendrocytes in the central nervous system.

The human immune system is our natural defense against infections and abnormal cells like cancer. It relies on a carefully balanced network of genes that produce receptors, signaling molecules, and transcription factors—all influenced by en…

ORGESTRA is a Joint Doctoral Network training thirteen PhD researchers in organoid technologies for disease modelling, drug discovery and clinical development for rare diseases including cystic fibrosis and cystinosis. An innovative trainin…

The overall research aim of BullNet is to use cutting-edge molecular and machine-learning techniques, coupled with functional and applied methods to unravel the underlying sperm biology surrounding compromised fertility of individual bulls,…

Today, ion mobility–high-resolution mass spectrometry (IM-HRMS) is a state-of-the-art analytical platform that can measure and quantify molecules that are central to experimental sciences across disciplines. However, it still faces barriers…

The GLYCO-N training network aims at training Doctoral Candidates (DCs) to acquire the skills to develop different innovative strategies to 1) understand the diversity and structural complexity of archaeal, microalgal and viral N-glycosylat…

Context and Objectives Carbohydrates mediate critical biological processes, yet natural Carbohydrate-Binding Molecules (CBMs) used to target them are costly, delicate, and often lack selectivity. The ENSCC project addresses this problem by…

Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers and continues to show limited response to current therapeutic approaches, including immunotherapy. Novel therapeutic approaches capable of overcoming tumour immune…

Large bone defects caused by trauma, disease, or ageing represent a growing clinical challenge in Europe, particularly in an ageing population. Current treatments heavily rely on bone grafts taken from the patient or donors, which are limit…

Sepsis remains one of the major challenges for societies worldwide, causing an estimated 7-9 million deaths every year. It is the leading cause of death at intensive care units in the EU.

Alzheimer’s disease (AD) is a common debilitating age-related neurodegenerative condition characterized by progressive cognitive decline and pre-symptomatic accumulation of amyloid-β. Over 14 million people in Europe are living with dementi…

Glioblastoma is among the most aggressive malignant brain tumours in adults and remains associated with limited treatment options and poor survival. While immunotherapies have transformed treatment in several cancers, their success in gliob…

Modern society depends on the rapid discovery of new molecules for health, materials and sustainable technologies. Yet building molecular complexity still often requires long synthetic sequences, and late-stage modification of advanced mole…

CONTEXT | Esophageal adenocarcinoma (EAC) is a rapidly increasing cancer in Europe that still lacks effective, tailored treatments and clear, uniform care pathways. There is an urgent need for better therapies, tools to match the right trea…

Antimicrobial resistance (AMR) has escalated into a global health crisis, with more than one million estimated deaths in 2019 attributable to infections with antibiotic resistant pathogens. Gram-positive bacteria are responsible for a large…

MetacMed addresses a major gap in Europe’s innovation ecosystem: the translation of advanced acoustic and mechanical metamaterials (MMs) from laboratory research into practical solutions for healthcare, energy harvesting and noise reduction…

ProgRET is a multidisciplinary and intersectoral European training network focusing on the mechanisms, diagnosis and therapy of dominantly inherited retinal diseases (IRD). IRD represent a major cause of blindness, affecting 350,000 people…

The MIRACLE programme brings together leading academic and biotech industrial partners to train the next generation of innovation-minded researchers who can advance precision medicine approaches for cardiometabolic diseases (CMD). CMD are a…

When our ancestors began walking upright millions of years ago, the human pelvis underwent a dramatic transformation. This shift to bipedalism — walking on two legs — was one of the defining moments in human evolution, but it came at a cost…

DesiRTA: A Targeted Nanotherapeutic Approach for Revolutionizing Arthritis Treatment Arthritis, a prevalent global health concern affecting over 350 million individuals, substantially burdens healthcare systems. This chronic condition, char…

Antibiotics are now recognised as pollutants of global concern. Their widespread use has led to residues in the environment that contribute to antimicrobial resistance (AMR), a major threat to public health and ecosystems.

The longer average lifespan in our modern society is accompanied by a global increase in the prevalence of dementia, with Alzheimer’s disease (AD) being the most common cause. By 2050, the number of individuals with AD is expected to double…

Obesity has become a global epidemic and remains one of the most urgent public health challenges worldwide. Its rise has been accompanied by a marked increase in obesity related comorbidities, including type 2 diabetes, hypertension, and ca…

Physical technologies are playing an increasing role in medicine; among these, cold (gas) plasma – partially ionized gas generated at near‑body temperature – shows promise, especially in dermatology. Based on positive clinical results in wo…