infectious diseases

BOPA · Characterisation and engineering of the biosynthetic pathways of two model pyrrole amide antibiotics, congocidine and distamycin

TURBCONC · Fundamental and conceptual aspects of turbulent flows

IRON METABOLISM · Regulation of iron metabolism

PHARMAMAL · Investigation of the mechanism of action of antimalarial agents, by means of computational methods. Bases for the rational design of new antimalarial drugs

MALKINRAB · Regulation of the Rab GTPases by phosphorylation in Plasmodium falciparum

SZAKONYI · Structural and functional studies of different bacterial multi-drug resistance proteins of DMT and MOP super-families

DC-SIGN LOCALIZATION · The identification of the cellular localization of DC-SIGN following interaction with HIV and other ligands

MESAIP · Metabolomics of salicylate induced plants

VWFMAL · The role of von Willebrand Factor (VWF) in malaria pathogenesis

HIVSNP · Host determinants of susceptibility to HIV-1 infection

CAVEOLINS · Caveolae and Caveolins: Integrating signals for airway smooth muscle cell proliferation

2 partners · 2 countries

MOLECULARCLOCK TOOLS · Development of tools for the analysis of molecular clock and their application for a case of Hepatitis C Virus epidemics with known infection history

SIGNALPATH · MAP kinase cascades controlling virulence in fungi: from signals to pathogenicity response

10 partners · 6 countries

HUMPROTHER · New tools for delivering therapeutic proteins: application to human therapy

HUMAN TSLP · Functional characterization of the novel human cytokine TSLP and its role in health and disease

NEW ABCS IN LEISHMAN · Functional and biochemical characterisation of novel ABC transporters of biomedical interest in the protozoan parasite Leishmania

CANTRAIN · Host-pathogen interaction systems as tools to identify antifungal targets in C. Albicans and C. Dubliniensis

12 partners · 10 countries

VIRAL IMMUNE EVASION · Using viral inhibitors to characterise signalling pathways involved in interferon induction

HIV EC COMPLICATIONS · Role of poly (ADP-ribose) polymerase and oxidative stress in cardiovascular complications of HIV infection

C.T.R.M.P.I.C. · Cross Talk between Resistance Mechanisms to Pathogen Infection in Cereals

SOXCITS · New and Environmentally Friendly Methods for Making Compounds with Medicinal Importance: Novel Singlet Oxygen Chemistry Combined with Cascade Reactions for the Synthesis of Bioactive Natural Product

MBLUKP · Clinical consequences of mannose binding lectin dysfunction.

LABHEALTH · Novel applications of lactic acid bacteria to improve food safety and health

GALAR FUNGAIL II · Interaction of fungal pathogens with host cells: a post-genomic approach

10 partners · 6 countries