drug discovery

CAMPY SECRETION · Comparative Proteomics and Function of Secreted Proteins of Campylobacter jejuni

HESC METABONOMICS · Elucidation of Stem Cell Fate and Cell-type Characterization by 1H-NMR-based Metabonomics

SMART · Small Molecule Antagonists of chromatin modifying enzymes for Regulation of Transcription, proliferation and differentiation

PHARMACOGENOMICS · Targeting multidrug resistant cancer

VSCHEMOPROTANNO · Virtual screening applied to chemogenomics and protein annotation

2 partners · 2 countries

AMINO HYDROXY ACIDS · A new approach to synthesis of b,a-amino hydroxy acids

TRIPR · Translational reserach in paediatric rheumatology

ANTICANCER NMR · Structural & dynamical characterization of the pro-metastatic enzyme heparanase for the designing of novel inhibitors

CHEMOFLUXOME · Development of metabolomics and fluxomics methods for metabolic drug target and toxicity elucidation using yeast

AVP-V2R · Function and regulation of the type 2 vasopressin receptor and 'V2R' in body fluid homeostasis

MEMPROT · The technologies of biological membranes

SIRNA-HCS · Study of the molecular mechanisms of cell migration by using high content screening and siRNA technology

3 partners · 2 countries

BIOMARKER DISCOVERY · Novel post-genomic bioanalytical techniques of metabonomics (metabolomics) in biomedical research and drug discovery

2 partners · 2 countries

ASTHMA · Micro-fluidic Biochips for trans-endothelial migration of eosinophils for the study of asthma

2 partners · 2 countries

SPIROTENUIPESINES · Total Synthesis of the Potent Neurotrophic Factors Spirotenuipesine A and B

2 partners · 2 countries

P53MUT. REACTIVATORS · Computer-assisted drug discovery and biophysical characterisation of mutant re-activators of the transcription factor p53 as putative tumour therapeutics

PEPTIDE QUANT · Quantification of bioactive peptides by mass spectrometry - Applicability in drug discovery

PLK1 INHIBITION · Inhibition of Cancer by Disrupting Interaction Between Polo-like Kinase 1 Polo-box Domain and Spindle Targets

IOIDMC · Identification of interacting domain of mammalian cryptochrome with clock proteins, BMAL, Period, and CLOCK

TRIFLU · Synthesis and properties of trifluoromethylated Carbo- and Heterocycles

NLRS IN IMMUNITY · NLR-proteins in Immunity and Inflammation

BIOMEDCHEM · Training for new approaches in anti-parasite and anti-tumour drug discovery

ANTIBIOTARGET · Molecular and functional genomic approaches to novel antibacterial target discovery

5 partners · 4 countries

ENZYME MICROARRAYS · An integrated technology for the deconvolution of complex biochemical systems, drug discovery and diagnostics