genetic engineering

DROSOPHILA TELOMERES · Drosophila Telomere Heterochromatin: Gene silencing and Telomere targeting

APOLIPOPROTEIN E · Functional interactions of apolipoprotein E with the ABCA1 lipid transporter and the SR-BI HDL receptor that affect cholesterol homeostasis in circulation and brain

CYTOLYTIC SYNAPSE · Regulation of cytotoxic T lymphocyte activity at the lytic synapse

SGT FOR GVL · Safe and effective immunotherapy of leukaemia with suicide gene-modified human T lymphocytes retaining anti-minor histocompatibility antigen reactivity

PORCINE CD200 · Study of the CD200/CD200R pathway in the pig-to-human setting to elucidate the molecular bases of xenograft rejection and develop approaches that promote xenograft survival.

HARUCHAN · Development and application of novel LD-based approaches for the positional cloning of quantitative trait loci in livestock

INSULAGE · Understanding the interplay of insulin/IGF signalling with endocrine hormones in ageing

IMDEMI · Innovative mouse models for functional genomics in immunology

9 partners · 4 countries

SEMAPHORINSANDCANCER · The role of semaphorins and plexins in cancer progression and angiogenesis

LYMPHANGIOGENOMICS · Development and use of a novel Xenopus model to study functional lymphangiogenomics

ALLELO-SIGNALLING · Dissection of signal transduction cascades regulating inter and intra-species interactions among phytoplankton assemblages in the marine environment

MAFOSE · Mannoproteins in food security

TRANSFECTAZINE · Low-toxicity azine-based cationic lipids for gene transfection

DEMISE · Mitochondrial pathways in neurodegeneration

STEROTRANS · Anion Transport by Steroid-Based Synthetic Channels

AIM · Antibody Immunotherapy for Malaria

TEAMOHOLIC · Team on Advanced Transgenic Animal Technologies

RETNET · European Retinal Research Training Network

7 partners · 5 countries

IMAGING SYNAPTIC ACT · Synaptic modulation during olfactory perception in Drosophila melanogaster

BIFIDOGT · Towards gene therapy using Bifidobacterium as gene delivery system

GENE THERAPY PARKINS · Gene therapy for treatment of Parkinson's disease : functional and cellular evidence

BENJAMIN MARTIN · Dynamic and targeted vectors for gene transfer

Spatio-temporal controlled gene delivery and expression for non viral gene therapy

Development of triggered endosomolysis mechanism for improved gene therapy