proteins

Biosensor Design · Engineering Chemotactic Biosensors for a Diverse Spectrum of Metastatic Markers

IMaP · Imaging tumor vessels as a marker for p53 mutation status in cancer

EnCAge · Progeria models to study endothelial cell ageing: implications for organ regeneration and fibrosis

OCTOBER · Control of cell identity in pluripotent and germline cells by OCT4 orchestration of chromatin binding and enhancer regulation

IMMUNE · Investigation into the Molecular Mechanisms Underlying NEmatode recognition by the Ma resistance protein in perennial plum roots

CSI AurkA-MYC · Conformational Shift Inducers (CSI): An atomistic level investigation of Aurora kinase A (AurkA)–MYC interaction and its distortion by CSI compounds

SAND · Secretion, Autophagy and their role in Neurodegeneration

17 partners · 10 countries

PROTON · Proton transport and proton-coupled transport

13 partners · 8 countries

UBIMOTIF · Short linear interaction motifs as specificity determinants in the ubiquitin system – discovery, mechanisms and therapeutic opportunities

11 partners · 8 countries

SECRET · Exploitation of the SECRETory pathway for cancer therapy to address European research

12 partners · 8 countries

AntiHelix · DNA helicases in genome maintenance: from molecular and cellular mechanisms to specific inhibitors as potential drugs

9 partners · 6 countries

MetALS · Investigating the pharmacokinetic properties of toxic metals and heat shock proteins as risk factors in Amyotrophic Lateral Sclerosis

Light4Sight · Light-activated carriers for the controlled delivery of therapeutic peptides in posterior segment eye diseases

FunStructure · Interdependence of functional and structural plasticity in cerebellar climbing fibers in health and disease

Monopoly · Baeyer Villiger Monooxygenases as Biocatalytic Parts for Monomers of New Lactone-based Polymeric Materials

ProTeCT · Proteasome as a target to combat trichomoniasis

2 partners · 2 countries

THIAZOLIUMenzyme · Enzyme design and engineering by implementation of non-canonical amino acids in protein scaffolds

AL4BIOCH · Assembly Lines for Biocombinatorial Chemistry

PhotoXLink · Development of biomolecular tools for the spatiotemporal photocontrol of AMPA receptors mobility

ASSEMBLY · Advancing Synthethic Supramolecular chemical biology

ALCO-ADO · Unveiling the alcohol-dependent alterations in local dendritic translation of mRNAs in the prefrontal cortex during adolescence

EcoNoMy · Economy of Non-Elite Mycenaeans

GPCR Transcriptomics · Exploring the role of GPCR expression diversity in receptor physiology and drug response

GlycoMabs · Chemoenzymatic glyco-engineering of therapeutic monoclonal antibodies