biomolecules

INFLACOMM · Interplay of inflammasomes, commensals and pathogens at mucosal interfaces

6-SENSE · The role of NLRP6 sensing in regulation of intestinal host-microbiome interactions

TRIGBM · Identification of TRAIL sensitivity/resistance mechanisms and searching for novel TRAIL-sensitizing agents in Glioblastoma Multiforme

MODULATOR · Detailed binding scheme and structural determination of the 14-3-3ζ in complex with a double phosphorylated human tyrosine hydroxylase 1

VIROMA · Design of a versatile and fast colloidal sensor based on virus modified particles

3 partners · 2 countries

PlantAgeing · Deciphering the regulatory role of reactive oxygen species in plant ageing through an integrative genetics and genomics approach

2 partners · 2 countries

LSD1 IMPACT · Dissecting the interaction network of the histone demethylase LSD1 in vivo

NANOCAGE · The Development of Protein Cage-Based Inorganic Nano-Materials (resubmission)

NER · Structural studies of Nucleotide Excision Repair for drug development targeting protein-DNA interactions

3W-RGB · Identification of whether, in which aspects and by which function, a RNA binding protein, KH-type splicing regulatory protein governs development and function of B cell, a type of white blood cell""

SERPLUC · Suppression of Enzymes Required for Progression of LUng Cancer

T-BAC · Exploring the roles and plasticity of T-cell responses in anti-BACterial immunity

SMURF2 IN CANCER · Molecular mechanisms of tumor suppressor functions of HECT-type E3 ligase Smurf2: roles in chromatin organization, dynamics, gene expression and DNA damage response and repair

TOPIC · Targeting Cytotoxic Protein Oligomers

2 partners · 2 countries

GLYCODRUGS · new strategies for controlling the activity of glycosidase enzymes and their application in therapies for lysosomal storage diseases and cancer

GSEC-AD · Subcellular localization of distinct γ-secretase complexes defines substrate specificity

NCAT · Nudix hydrolases in Cancer Therapy

BIOENERGY · Biofuel Cells : From fundamentals to applications of bioelectrochemistry

13 partners · 8 countries

PrOSt! · Development of low-calorie beverages with prebiotic properties from cheap and abundant feedstocks

PlasticAstros · Plasticity at the tripartite synapse: an in vivo study of astrocyte-synapse interactions in the mammalian cortex

HumanRib · metal ion binding - stucture - function relations of the human CPEB3 ribozyme

BAGEL · Bacterial Formation of Glycerol (di)Ether Lipids: Biogeochemical, (paleo)environmental and evolutionary implications

DENDRITE2BEHAVIOR · From dendrite to behavior: fiberoptic Imaging and optogenetic manipulation of dendritic activity in behaving animals

BONEMETTNC · Analysis of Tenascin C function in breast cancer metastasis to bone