biomolecules

MOL-MENATB · Molecular approach to the study of antibiotic susceptibility of Neisseria meningitidis and of its impact on pathogenesis of meningococcal infection

SKI IN SCHWANN CELLS · Functions of the proto-oncogene Ski in the regulation of TGFbeta signalling and the control of Schwann cell proliferation, differentiation and apoptosis

PLANT CDD COMPLEX · Role of the plant DDB1 complex in chromatin remodelling at loci of UV damaged DNA and developmental genes

GLYCOENGINEERING · Enzymatic engineering of modified Glycostructures

DSCC · Design, synthesis and characterisation of Conotoxins

SPIROTENUIPESINES · Total Synthesis of the Potent Neurotrophic Factors Spirotenuipesine A and B

2 partners · 2 countries

ULTRA-FAST FOLDING · Dissecting folding pathways of highly homologous, ultra-fast folding proteins

TILTED PEPTIDES · Molecular biophysical study of tilted peptide-lipid interactions in lipid bilayers and their application in membrane fusion

HIGH-THROUGHPUT PROX · Global analysis of DNA-protein interactions by sensitive proximity-dependent DNA ligation assays and tag arrays

TBID,CL AND CYT C · Mitochondrial membrane reorganisation induced by tBid during apoptosis: cardiolipin and cytochrome c redistribution analysed by single molecule spectroscopy and microscopy

FAPR · Global regulation of lipid biosynthesis in Gram-positive bacteria: structural and biochemical characterization of FapR

FLUHET · Fluorinated Heterocycles from Organosilanes: Novel synthetic approaches towards Fluorinated Lactones

PROT.OX. AND HSPS · Is heat shock protein mediated protection against ageing and protein oxidation tissue specific?

2 partners · 2 countries

UNCOUPLING PROTEINS · Function and evolution of uncoupling proteins in Drosophila melanogaster

2 partners · 2 countries

NOVOSTEM · Deprogramming of the mammalian genome for stem cell production

2 partners

SCIOSLUGCONTROL · The potential use of sciomyzid flies as novel biocontrol agents of pest slugs in Europe and the USA, with particular reference to Ireland and California

2 partners · 2 countries

SMC COMPLEXES · The architecture of Smc complexes and their functional roles in chromosome maintenance

MOUSE MELANOMA MODEL · Characterization of novel acting mechanisms of the Hepatocyte Growth Factor (HGF) in melanomagenesis: Bring into play the HGF transgenic animal model

3DCAP · Three-dimensional genomic analysis of cancer progression

NALP3 AND MDP · Role of the NALP3-inflammasome activation by muramyl dipeptide in vivo

HCVCORE2005 · Molecular characterization of the HCV core protein mobility to/from lipid droplets and its role in their formation

KNOX TARGET GENES · Identification and characterization of target genes regulated by KNOX transcription factors in different plant species

MEPOLHAIR · Participation of endomembranes and components of the cell wall on the maintenance of plant cell polarity

DPP6 AND 10 PARTNERS · Investigate for cellular partners of DPP6 and DPP10 through novel technologies