biochemistry

FORCECHAPERONES · Chaperones mediated mechanical protein folding

MYOII-DRIVEN FISSION · Reconstitution of Myosin IIA-driven membrane fission in vitro

SMART · Shedding microvesicles as drug loaded Trojan horses (SMART) – an exploration of unique drug carriers using a versatile enzyme nano assay

NanoSwitchingDynamic · Direct Nanosecond and Nanometer Scale Investigations of Nucleation and Growth Phenomena

IMPACT · Improved Millets for Phosphate ACquisition and Transport

AquaCat · Tailor made lipases for synthetic catalysis in biphasic media: From poly (lactone) applications towards novel sugar esters

Homomers · Exploiting homomers to reveal new principles of protein interaction, polymerization and aggregation

LYMFOXP1 · ROLE OF THE TRANSCRIPTION FACTOR FOXP1 IN B CELL FUNCTION AND LYMPHOMAGENESIS

INFLACOMM · Interplay of inflammasomes, commensals and pathogens at mucosal interfaces

6-SENSE · The role of NLRP6 sensing in regulation of intestinal host-microbiome interactions

TRIGBM · Identification of TRAIL sensitivity/resistance mechanisms and searching for novel TRAIL-sensitizing agents in Glioblastoma Multiforme

MODULATOR · Detailed binding scheme and structural determination of the 14-3-3ζ in complex with a double phosphorylated human tyrosine hydroxylase 1

VIROMA · Design of a versatile and fast colloidal sensor based on virus modified particles

3 partners · 2 countries

PlantAgeing · Deciphering the regulatory role of reactive oxygen species in plant ageing through an integrative genetics and genomics approach

2 partners · 2 countries

LSD1 IMPACT · Dissecting the interaction network of the histone demethylase LSD1 in vivo

NANOCAGE · The Development of Protein Cage-Based Inorganic Nano-Materials (resubmission)

NER · Structural studies of Nucleotide Excision Repair for drug development targeting protein-DNA interactions

3W-RGB · Identification of whether, in which aspects and by which function, a RNA binding protein, KH-type splicing regulatory protein governs development and function of B cell, a type of white blood cell""

SERPLUC · Suppression of Enzymes Required for Progression of LUng Cancer

T-BAC · Exploring the roles and plasticity of T-cell responses in anti-BACterial immunity

SMURF2 IN CANCER · Molecular mechanisms of tumor suppressor functions of HECT-type E3 ligase Smurf2: roles in chromatin organization, dynamics, gene expression and DNA damage response and repair

TOPIC · Targeting Cytotoxic Protein Oligomers

2 partners · 2 countries

GLYCODRUGS · new strategies for controlling the activity of glycosidase enzymes and their application in therapies for lysosomal storage diseases and cancer

GSEC-AD · Subcellular localization of distinct γ-secretase complexes defines substrate specificity