mutation

MARKTHEPIG · Applied phenomics to identify biomarkers in pigs for new concepts in precision livestock farming

Spotifly · Genetic paths underlying the convergent evolution of pigmented spots on fly wings

channelopathies · Type 1 reyanodine receptor Structure and regulation by post-translational modifications and small molecules.

SATBIOFUN · Genome editing for spatiotemporal analysis of centriolar SATellite BIOgenesis and FUNction in cellular stress responses

2 partners · 2 countries

F-ATPase · Towards a Complete Quantitative Model of the FOF1 ATP Synthase

NovLeuReg · Identification and characterization of novel essential regulators of acute myeloid leukemia

SpliceosomeStructure · Structural role of protein splicing factors in promoting an active configuration of the spliceosome's RNA catalytic core

Molmechindividuality · Molecular mechanisms of neuronal connectivity - the synaptic code for variability and stereotypy

2 partners · 2 countries

RAGES · Molecular determination of Rif1-Associated Genomic Elements and their function in regulating genome activity and integrity

MoTOR · Analysis of the “moonlighting” proteins in the mTOR-signalling pathway

EMBCC · Evolution of mutator bacteria in a community context

switchBoard · In the eye of the observer: Visual processing at the heart of the retina

15 partners · 9 countries

MOvE-ECG · Moving from genome wide association to elucidating causal mechanisms of electrocardiographic traits

2 partners · 2 countries

SOX10mutants · Investigating genotype-phenotype correlations in SOX10 neurocristopathies

NMJALS · In vivo analysis of neuromuscular junction stability in zebrafish models of amyotrophic lateral sclerosis

HepatoRiSK · A new tumor suppressor role for RSK2 in hepatocellular carcinoma

PFSEXOME · Identification of protein kinases and signalling pathways important for Plasmodium falciparum malaria transmission

2 partners

APOBEC · Enzymatic DNA deamination and the immunity/cancer balance

SFSASP · Structural and Functional Studies of ATRX- Syndrome Protein

MDR Tuberculosis · Evolution and success of the multi-drug resistant M. tuberculosis SIT41 (LAM7-TUR) lineage

BRIDGES · Bioinformatic approaches to identify and detect both disease- and drug-related genomic alterations in breast cancer patients

SorCSbalance · Role of the sorting receptor SorCS1 in controlling excitation/inhibition balance in neural circuits.

CICCI · Characterization of Intestinal Cancer Cell Invasion

FCSM · Human myosins