mutation

TRKB AND OB-R · Functional characterization of TrkB and Ob-R mutations identified in severely obese children

ZCLOCK · Analysis of the Molecular mechanisms controlling the Segmentation Clock during Zebrafish Somitogenesis

2 partners · 2 countries

NCT-BINDING · Substrate docking and affinity studies of Nicastrin: the binding mechanism

VPLANS_DD_CLC-5 · ClC-5 regulation and endocytosis at the renal proximal tubule or molecular bases of Dents disease

MYO-PATHOGENESIS · Gene discovery and disease pathogenesis in the inherited myopathies

2 partners · 2 countries

BIOCELLCHARABRX · Biochemical and cell biological characterization of BRX, a novel regulator of root architecture in Arabidopsis, and its role in hormone homeostasis

MCP-1 AND PODOCYTES · Role of the MCP-1/CCR2 system in the podocyte alterations of Diabetic Nephropathy: an in vivo and in vitro study

MEMPROT · The technologies of biological membranes

SACKI · Cross-kingdom investigation of the mammalian retroviral silencing suppressor Tas to identify novel silencing factors

AGING AND CANCER · Aging and cancer

PD-MITOCHONDRIA · Parkinson's disease and mitochondria dysfunction

KNOTTEDPROTEINFOLD · A tangled problem: how does a knotted protein fold?

MOL-MENATB · Molecular approach to the study of antibiotic susceptibility of Neisseria meningitidis and of its impact on pathogenesis of meningococcal infection

P53MUT. REACTIVATORS · Computer-assisted drug discovery and biophysical characterisation of mutant re-activators of the transcription factor p53 as putative tumour therapeutics

UNCOUPLING PROTEINS · Function and evolution of uncoupling proteins in Drosophila melanogaster

2 partners · 2 countries

NALP3 AND MDP · Role of the NALP3-inflammasome activation by muramyl dipeptide in vivo

KNOX TARGET GENES · Identification and characterization of target genes regulated by KNOX transcription factors in different plant species

ZP DOMAIN STRUCTURE · Structure determination of the zona pellucida domain by X-ray crystallography

STATINFPOPGEN · Statistical inference in population genetics

ENDOCYTE · The intracellular routes of growth factor signalling from the plasma membrane to the nucleus

11 partners · 8 countries

AV IDENTITY IN ESCS · Specification of Arterial Venous Identity in Embryonic Stem Cells

PROSA · European Network on selection and analysis of protein-protein Interactions

11 partners · 7 countries

AURORAA_MOUSE_MODELS · Aurora A mouse models: new tools for the study of mitosis deregulation in cancer

NR4A2 TARGETS · NR4A2 target genes important in Parkinson's Disease