Neurofeedback · Modulating Human Brain Function and Dysfunction with Neurofeedback
7РП — „Хора“ (Действия „Мария Кюри“)
- Период
- 2012-01-01 → 2014-12-31
- Финансиране от ЕС
- 75 000 €
- Участници
- 1
- Схема
- MC-CIG
Линиите свързват координатора с партньорите.
Накратко на български
Неврообратната връзка чрез fMRI позволява на хората да контролират съзнателно активността в мозъка си, например в мрежите за емоции. Това помага за по-доброто разбиране на мозъчните функции и предлага нов метод за терапия при неврологични и психиатрични разстройства.
Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.
Резултати накратко
Modulating Human Brain Function and Dysfunction with Neurofeedback.
We proposed to investigate causal links between brain activity and mental functions with real-time fMRI based neurofeedback. This new technique allows us to teach participants to voluntarily regulate the level of their brain activity and to subsequently test how self-regulating brain activity affects mental functions and behavior. To achieve these objectives, we have now fully implemented a real-time functional magnetic resonance imaging (fMRI) setup at the Brain & Behavior Laboratory at the University of Geneva, and at the Center for Biomedical Imaging at the Swiss Institute of Technology Lausanne (EPFL). These setups have now been used to develop an approach to provide neurofeedback based on connectivity between brain areas (rather than activity within a brain area). The connectivity-based approach allows us to better target neurological conditions that are associated with abnormal patterns of functional brain networks. We successfully used this new approach to train healthy participants and patients control over their visual brain networks, as well as over their emotion networks. Further, we have shown that neurofeedback training effects are maintained for at least 12 months, and that strategy guidelines facilitate neurofeedback learning. These accomplishments will significantly improve the specificity and effectiveness of the neurofeedback approach as a promising method to investigate human brain function and as a novel experimental therapy for neurological and psychiatric disorders.
Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз
Цел на проекта
Neuroimaging allows to characterize patterns of neural activity that specifically correlate with mental functions such as perception, memory, and emotions. However, conventional imaging experiments are purely observational and cannot be used to establish a causal link between brain activity and the mental functions that are studied. Here I propose using a new approach to investigate causal links between the two: I will use real-time functional magnetic resonance imaging (rtfMRI) with neurofeedback to teach participants to voluntarily regulate either the level of brain activity or of the functional coupling of brain areas. I will then test how self-regulation of activity (or connectivity) affects perception and memory, thus allowing an understanding of the causal relationship between the two.Using neurofeedback, I will (a) test how self-regulating brain connectivity in the visual cortex affects visual feature integration, (b) explore the use of neurofeedback to treat patients with visual hemispatial neglect, which is a common and disabling neurological disorder, and (c) use neurofeedback to manipulate visual memory consolidation by indirectly affecting neurotransmitter systems. Besides these three main projects, I will significantly advance the field of rtfMRI-based neurofeedback by (a) extending the neurofeedback approach to control functional brain networks instead of only a single area (connectivity feedback), and by investigating (b) how long learned self-regulation is maintained without further training, (c) if self-regulation causes structural changes in brain anatomy, and (d) how important strategy guidelines are for learning self-regulation.These projects will provide new insights into the causal links between brain activation and mental functions, and they will also provide important methodological innovations which will lay the foundation for valuable clinical applications.
Оригинален текст от CORDIS (на английски).
Участници
- UNIVERSITE DE GENEVE · GeneveКоординаторШвейцария
Връзки
Данни: CORDIS, © Европейски съюз