BIOLAS · Development of Novel Biological Lasers based on Fluorescent Proteins, Live Cells, and Self-Assembled Resonators
7РП — „Хора“ (Действия „Мария Кюри“)
- Период
- 2013-08-01 → 2017-07-31
- Финансиране от ЕС
- 100 000 €
- Участници
- 1
- Схема
- MC-CIG
Линиите свързват координатора с партньорите.
Накратко на български
Биологичните лазери се изследват чрез използване на живи клетки, програмирани да произвеждат флуоресцентни протеини. Това помага за създаването на нови фотонни инструменти и по-добро разбиране на светлинното излъчване в живите системи.
Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.
Резултати накратко
Development of Novel Biological Lasers based on Fluorescent Proteins, Live Cells, and Self-Assembled Resonators
Biological structures with optical functionality have fascinated mankind for generations. Their application for bioinspired and bioderived optical devices might enable new photonic tools. An example of such a novel biooptical component is the biolaser that was developed by the Fellow. In this type of laser, coherent emission is generated e.g. by a single biological cell that is genetically programmed to produce a fluorescent material (the so called green fluorescent protein, GFP). During the integration grant, the fellow has worked on developing a better understanding of lasing and stimulated emission in biological materials and systems, improving the performance of biolasers, and developing new applications. The focus was initially on investigating biologically derived gain media, in particular different fluorescent proteins, and their in vitro characteristics as laser materials. Moreover, in vivo lasing based on cells expressing fluorescent proteins was studied in detail. Suitable resonators for completely natural lasers, in particular self-assembled structures, were investigated. While several other groups, including outside Europe, have become strong competitors over the past years, the integration grant has helped to maintain and cement the fellow competitive edge in the field. Synergies between work on organic lasers, intensively studied at the Fellow’s host institution, and the recently invented biolasers have rendered integration at the chosen host institution particularly successful.
Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз
Цел на проекта
Biological structures with optical functionality have fascinated mankind for generations. In the future, their application for bioinspired and bioderived optical devices might enable new photonic tools. An example of such a novel biooptical component is the biolaser that was recently pioneered by the Applicant. In this type of laser coherent emission is generated by a single biological cell that is genetically programmed to produce a fluorescent material (the so called green fluorescent protein, GFP). Current biolasers, however, are quite inefficient and require both an artificial resonator and an external pump source. The Applicant’s long-term goal is to establish whether laser light can be generated completely independently within a living organism. During the integration phase, the Applicant will develop a better understanding of lasing and stimulated emission in biological materials and systems and improve the performance of these lasers. The focus will initially be on investigating biologically derived gain media, in particular different fluorescent proteins, and their in vitro characteristics as laser materials. Moreover, in vivo lasing based on cells expressing fluorescent proteins will be studied in detail and self-healing of lasers will be demonstrated. Suitable resonators for completely natural lasers, in particular self-assembled structures, will also be investigated. The Applicant currently has a competitive edge in the field but other groups, especially outside Europe, are expected to become strong competitors over the next years. The integration phase thus constitutes a unique opportunity to establish a strong position in this truly novel field within Europe. Synergies between work on organic lasers, intensively studied at the Researcher’s new host institution, and the recently invented biolasers render integration at the chosen host institution particular attractive.
Оригинален текст от CORDIS (на английски).
Участници
- THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS · ST ANDREWSКоординаторОбединеното кралство
Връзки
Данни: CORDIS, © Европейски съюз