H2020Обмен на изследователи2015–2018

GoMyTri · Golden Mycological Triangle – joining forces to exploit mycological biodiversity for novel anti-infectives and other beneficial metabolites

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период
2015-01-01 → 2018-12-31
Финансиране от ЕС
333 000 €
Участници
3
Схема
MSCA-RISE

Линиите свързват координатора с партньорите.

Накратко на български

Гъбите и микроорганизмите в Европа и Югоизточна Азия се анализират за откриване на нови антибиотици и биологично активни вещества. Тези проучвания помагат за разработването на лекарства срещу инфекции и създаването на безопасни алтернативи на химикалите в земеделието.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Golden Mycological Triangle – joining forces to exploit mycological biodiversity for novel anti-infectives and other beneficial metabolites

The cooperation was intended to explore the mycological and microbiological biodiversity of Europe and Southeast Asia, in particular with regard to the search for the badly needed new antibiotics and other biologically active substances. It has various possible impacts on society, ranging from basic research on fungal evolution and ecology to drug research and development of new biological control agents to replace hazardous chemicals in agriculture. The project was conducted to foster international collaboration networks, know-how exchange and interdisciplinary training of young scientists. The partners are three research infrastructure organisations in Germany, the Netherlands and Thailand that are recognised internationally as strongholds in mycological, biotechnological and microbiological research. The medium term aim of the project, i.e., to attain a sustainable internationally visible strategic cooperation, including other departments of the institutions involved, has been accomplished because various new collaborations have already resulted from the working program and additional scientific working groups in the partner countries are actively involved. The quantitative goals of the working program were overachieved, and not even half of the novel bioactive metabolites discovered has so far been published. Moreover, numerous new fungal taxa that were identified among the newly isolated strains during the course of polyphasic taxonomic studies are still awaiting formal description. The project also included the dissemination of data and results in Internet-based public domain databases and through interdisciplinary workshops, as well as on international conferences, to increase the awareness of the public and the stakeholders in industry. The goal of reaching public awareness, in particular in the scientific community, has definitely been reached through publication of numerous scientific papers the presentation of the project results on various conferences. The highlight of the project dissemination was the 11th Mycological Congress in Puerto Rico (July 2018), where over 20 contributions of the participating scientists, including plenary lectures, poster presentations and workshop presentations, were included in the scientific programme. However, the evaluation of the new compounds and candidate biocontrol agents discovered is still at a rather early stage. Hence, industrial collaborations to develop these candidates have not yet been initiated.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

The proposed project aims at the intensification of cooperations between research infrastructure organisations in German, the Netherlands and Thailand that are recognised internationally as strongholds in mycological, biotechnological and microbiological research. The cooperation is intended to explore the mycological and microbiological biodiversity of Europe and Southeast Asia, in particular with regard to the search for the badly needed new antibiotics and other biologically active substances. The working plan includes activities such as the systematic exploration of fungal biodiversity by using modern molecular phylogenetic and chemotaxonomic techniques, as well as genome sequencing, in conjunction with classical microbiology. The focus of the research will be set on endophytes (in particular, Xylariaceae and Botryosphaeriaceae), invertebrate-associated ascomycetes (Cordycipitaceae), and marine fungi and fungal-like organisms, respectively. In addition, some basidiomycete cultures will also be studied. Between the participating partners already exist very good personal contacts and smaller research collaborations, which will be intensified in the context of the proposed project. Several staff exchanges and workshops are planned, which should allow the partners to further increase and optimise their interactions and to attain interdisciplinary skills. In the medium term the project is aimed at attaining an internationally visible strategic cooperation, including other departments of the institutions involved.

Оригинален текст от CORDIS (на английски).

Участници

  • HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH · BraunschweigКоординаторГермания
  • KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW · AMSTERDAMНидерландия
  • NATIONAL SCIENCE & TECHNOLOGY DEVELOPMENT AGENCY · Klong 1 KlongluangТайланд

Връзки

Данни: CORDIS, © Европейски съюз