Меню
КартаВръзкиТемиБългарияНощта (K-TRIO)Мария Склодовска-КюриЗа ученициЗа учителиМетодологияИзненадай ме
H2020Обмен на изследователи2015–2019

TROPSENSE · Development of a non-invassive breath test for early diagnosis of tropical diseases

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период
2015-02-01 → 2019-01-31
Финансиране от ЕС
1 386 000 €
Участници
14
Схема
MSCA-RISE

Линиите свързват координатора с партньорите.

Накратко на български

Разработва се бърз тест за откриване на тропически болести като денге и лешманиоза чрез анализ на издишания въздух. Ранната диагностика е важна, защото тези инфекции имат неспецифични симптоми и могат да бъдат фатални без навременна терапия.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Development of a non-invassive breath test for early diagnosis of tropical diseases

Hydatidosis (cystic Echinococcosis), Leishmaniasis and Dengue are included in the list of 17 neglected tropical diseases elaborated by the World Health Organization (WHO), which are a group of tropical infections that are prevalent in the tropical and subtropical regions of Africa, Asia and the Americas, affecting especially the low-income populations in the developing areas. All these neglected tropical diseases generally cause unspecific symptoms, and they cannot be easily identified when a patient arrives at the hospital. The failure of an early diagnosis and prescription of an adequate treatment can be extremely negative and even fatal for the patient. The objective of our project is the development of a fast, inexpensive, and easy-to-operate diagnostics tool for on-site early detection of Hydatidosis, Leishmaniasis and Dengue, based on the analysis of exhaled breath composition.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

This project aims at demonstrating the feasibility of a non-invasive, safe and patient-friendly methodology for on-site rapid diagnosis of tropical diseases. The proposed approach is based on breath samples analyses, which are easy to obtain and present no discomfort or risk for patients health. In this study will be enrolled patients with three different types of neglected tropical diseases (Hydatidosis, Leishmaniasis and Dengue) from different geographical locations (Europe, South America and Maghreb). Breath sampling will follow a standardised procedure. Analytical chemistry methods will be employed for the identification of the breath volatile biomarkers of these diseases. A pool of potential nanomaterials with high affinity towards the identified VOCs will be selected (e.g., gold nanoparticles, carbon nanotubes and semiconducting nanowires, either pristine or functionalised with selected hydrophobic organic molecules and/or bio-molecules). For maximising the possibility of success of our methodology, we will investigate the synergic effect of different advanced and complementary chemical sensing techniques: Mid-Infrared Quantum Cascade Laser spectroscopy and different types of Chemical Gas Sensors devices. These techniques are particularly attractive, since they can be miniaturised and are suitable for building on-site portable systems. Advanced pattern recognition algorithms will be employed for building discriminative models for the identification of the fingerprints of the different tropical diseases studied, and multisensors data fusion will be then applied for obtaining enhanced resulyts. A point of care prototype will be proposed on the basis of the results obtained and validated on-site.

Оригинален текст от CORDIS (на английски).

Участници

Връзки

Данни: CORDIS, © Европейски съюз