H2020Индивидуална стипендия2015–2017

Spinal cord fMRI · Functional magnetic resonance imaging of the cervical spinal cord at 7 Tesla

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период: 2015-09-01 → 2017-08-31
Финансиране от ЕС: 183 455 €
Участници: 1
Схема: MSCA-IF-EF-ST

Линиите свързват координатора с партньорите.

Накратко на български

Методи за по-ясно изображение на шийния отдел на гръбначния стълб чрез силни магнитни полета (7 Тесла) се тестват в проекта. Високата разделителна способност помага за по-доброто изучаване на анатомията и функциите на тази тъкан при различни заболявания.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Functional magnetic resonance imaging of the cervical spinal cord at 7 Tesla

Magnetic Resonance Imaging (MRI) offers a unique possibility to study anatomy and function of neural tissue in humans without invasive procedures. The spinal cord is a part of the central nervous system and is implicated in a number of debilitating diseases. It is a small structure, measuring only about 1 cm in diameter at the level of the neck, and therefore requires high resolution imaging to study. With normal clinical MR scanners sufficient image resolution is difficult to achieve. MR scanners with higher background field strength (7 Tesla and above) give better signal-to-noise ratio, which can be used to achieve higher image resolution. Such systems are therefore well posed to study the spinal cord. However, they also introduce a number of additional technical challenges, especially related to spinal cord imaging. In this project, we have investigated methods for improving spinal cord imaging on 7 Tesla MR systems. The aim was to facilitate high-resolution anatomical and functional imaging of the spinal cord.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

Functional magnetic resonance imaging (fMRI) has become an indispensable tool in neuroscience to study human brain function non-invasively. However, translation of fMRI to investigate function of the second major component of the central nervous system, the spinal cord, has been severely hampered by technical difficulties. Two major challenges for spinal fMRI relate to the anatomy: (i) severe static image distortion caused by vertebrae and the lungs and (ii) dynamic signal instability introduced by breathing. I propose to address these problems by leveraging my expertise with cutting-edge technology for magnetic field compensation, available only to a few sites world-wide including my host institute in Oxford. These advances will enable me to take advantage of the signal-to-noise ratio improvement of ultra-high field (7 Tesla) MRI scanners, which has been clearly demonstrated in the brain but has remained elusive for the spine. The final stage of this project will deploy these methods on a collaborative project investigating the neurobiological mechanisms of pain in the spine. This project will enable me to build strategically on my dual training in engineering and medicine to develop an inter-disciplinary research profile at the interface of neuroscience and methodology.

Оригинален текст от CORDIS (на английски).

Участници

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD · OxfordКоординаторОбединеното кралство