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КартаВръзкиТемиБългарияНощта (K-TRIO)Мария Склодовска-КюриЗа ученициЗа учителиМетодологияИзненадай ме
H2020Докторантска мрежа2016–2019

MyFUN · Myopia: Fundamental understanding needed

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период
2016-01-01 → 2019-12-31
Финансиране от ЕС
3 544 115 €
Участници
9
Схема
MSCA-ITN-ETN

Линиите свързват координатора с партньорите.

Накратко на български

Механизмите на късогледството при младите хора се изследват чрез анализ на фактори като работата отблизо и липсата на дейности на открито. Разбирането на тези процеси помага за разработването на стратегии за превенция на заболяването и намаляване на риска от слепота.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Myopia: Fundamental understanding needed

In many countries of the world eyes of young people grow too long, developing myopia. Currently, about a third of the world population is myopic but it is expected that half of it will be myopic by 2050. In myopia, distance vision is compromised since the image is focused in front of the retina. Even worse, high degrees of myopia carry a significant risk of blindness for people at the peak of their professional careers, which imposes a severe economic burden to society. There is urgent need to develop preventive strategies for myopia development but many details about its mechanisms are still unknown. Studies have shown that myopia development is tightly linked to tense education and studies, near work and reduced outdoor activity. While studies in animal models have taught a lot about “the visual control of eye growth”, it remains strikingly unclear how exactly the visual experience looks like that accelerates eye growth in children and adolescents. In particular, there are no answers to questions like “If normal eye growth is tightly controlled by visual feedback, why does myopia not limit itself?” or “Why are the effects of new spectacle designs to inhibit myopia so small?” The ETN MyFUN, employing 17 international young scientists, tackled such questions. Their findings were published in international open access journals in currently 25 peer-reviewed articles. In summary, MyFUN was a very successful network contributing fundamentally to the understanding of myopia and its mechanisms.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

The proposed ETN “Myopia: fundamental understanding needed” (MyFUN) provides an international, interdisciplinary platform to train young scientists at the interface of physics and biology, to study unresolved questions about the visual control of eye growth. It has been extensively documented that the growth of the eye is controlled by closed-loop visual feedback, using retinal image defocus as an error signal. However, with tense education, predominant indoor activity and extensive near work, the eyes of young people grow too long and become near-sighted (myopic), reaching a prevalence of 95% in some Asian cities and 50% at German universities. While myopia is clearly a civilization disorder, it is strikingly unclear by which visual stimuli it is triggered, and how it can be stopped. Emerging optical interventions have still only moderate effects. There are fundamental questions, like “Why does myopia not limit itself?”, “Why does undercorrection not reduce its progression?”, “Why are the effects of new spectacle designs to inhibit myopia so small?”, “What determines when it starts and can we find biological markers to predict myopia in individual cases?”. We propose a scheme of novel experiments, divided into 14 research projects that all have sufficient scientific depth and merit to merge into 14 successful PhD theses. The answers to the research questions will fundamentally improve our understanding of myopia, will be recognized worldwide and will represent a major contribution of the European Community to the global problem of the rising incidence of myopia. Our consortium consists of 7 Beneficiaries, combining the expertise of 5 academic partners with excellent research and teaching records and 2 fully integrated private sector partners. MyFUN will be supported by a management team experienced in multi-site training activities and counselled by a scientifically accomplished External Advisory Board.

Оригинален текст от CORDIS (на английски).

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Данни: CORDIS, © Европейски съюз