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КартаВръзкиТемиБългарияНощта (K-TRIO)Мария Склодовска-КюриЗа ученициЗа учителиМетодологияИзненадай ме
H2020Обмен на изследователи2016–2019

MediHealth · Novel natural products for healthy ageing from Mediterranean diet and food plants of other global sources

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период
2016-01-01 → 2019-12-31
Финансиране от ЕС
1 224 000 €
Участници
13
Схема
MSCA-RISE

Линиите свързват координатора с партньорите.

Накратко на български

Растения от средиземноморската и световната диета се анализират за откриване на активни вещества с антиоксидантни свойства. Това помага за разработването на хранителни продукти, които поддържат здравето и намаляват рисковете от болести при стареенето.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Novel natural products for healthy ageing from Mediterranean diet and food plants of other global sources

Current demographic trends suggest a rapid increase in the percentage of elderly people in all European countries for the next 50 years. Increasing life expectancy of the general population bears the inherent risk of an increase of physical and mental impairments as well as of age-related diseases (e.g. cancer, neurodegeneration, metabolic complications etc.), posing a large and ever-growing burden on our societies if we fail to develop appropriate counteracting strategies. According to the WHO, by 2040, the global population aged 65 and over is estimated to reach 1.3 billion (14% of the total population). Consequently, the prevalence of age-related diseases will significantly increase. In this situation, the concept of healthy ageing, i.e. a strategy that allows people to grow old in good health, becomes very important. Numerous studies show that nutritional plant-derived compounds are involved in several physiological processes and possess significant beneficial effects on human health. Dietary plants, as medicinal plants, contain natural products that demonstrate powerful antioxidant properties and various biological activities. However, even if the beneficial effects of healthy eating are greatly recognized and globally acknowledged, the majority of food plants which comprise the ingredients of the most established dietary patterns haven’t been investigated in depth and consequently the active constituents remain unknown. MediHealth incorporated new technologies and methods in natural products discovery and isolation in order to discover natural entities from Mediterranean and global dietary plants, promoting healthy ageing. The final goal of the MediHealth project was to bring to the stage of development a novel nutraceutical product based on scientific evidences.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

The main goal of the MediHealth project is to introduce a novel approach for the discovery of active agents of food plants from Mediterranean diet and other global sources to promote healthy ageing. This will be achieved through an extended and well-balanced scheme of researcher’s secondments between 5 universities and 4 enterprises from EU & Associated countries as well as 4 universities from Third countries. A mutual scientific project developed on the needs and interests of both sectors exploiting the existing complementary expertise will be the base of this proposal. Plants from the Mediterranean diet and food plants from TC will be rationally selected and will be subjected to an integrated, interactive and comprehensive platform including in silico, in vitro (advanced cell-based assays), in vivo (flies and mice models) & metabolism assessment. Advanced analytical techniques will embrace the pharmacological evaluation process for the efficient isolation and identification of bioactive plant constituents. Pharmacological profiling of bioactive natural products as well as identification and synthesis of their metabolites will be carried out. Finally, to carry to the stage of development innovative products in the area of nutraceuticals/dietary supplements process-optimization studies will be performed. Within this project, core scientific multidisciplinary knowledge from different research areas will be integrated creating valuable synergies. Expertise will be transferred by means of the seconded researchers training in environments with different research orientation where complimentary skills are required. Special attention will be given to dissemination activities aiming to public awareness of benefits of healthy diet(s). MediHealth aspires to comprise a successful model promoting considerably researchers’ competences and long-lasting collaboration between Industry and Academia generating innovation potential at the European and global levels.

Оригинален текст от CORDIS (на английски).

Участници

Връзки

Данни: CORDIS, © Европейски съюз