NEURO-AGE · Addressing Neural Declines to Promote Healthy Ageing
„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“
- Период
- 2017-09-01 → 2019-08-31
- Финансиране от ЕС
- 172 800 €
- Участници
- 1
- Схема
- MSCA-IF-EF-RI
Линиите свързват координатора с партньорите.
Накратко на български
Способността за бърз избор на правилно действие, като спиране на автомобил на червен светофар, се променя с възрастта. Разбирането на тези процеси и свързаните с тях мозъчни зони помага за подобряване на качеството на живот при възрастните хора.
Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.
Резултати накратко
Addressing Neural Declines to Promote Healthy Ageing
The European Union estimates that by 2020, 1 in 5 Europeans will be at least 65 years of age. The increasing number of older adults presents challenges for society that have never been encountered before. Age-related declines in the ability to think, and the ability to control movements, lead to problems with everyday life, the ability of older people to live alone, and their ability to be part of our modern society. Developing approaches to understand and address age-related declines is therefore an important scientific challenge. The ability to quickly select the correct action to perform is essential to everyday life; for example, when driving a car, if we see a red light, it is essential that we can quickly choose the correct response of applying the brakes. This depends firstly on our ability to learn that we must respond to a red light by stopping, and secondly on our ability to make what we have learned automatic by practicing it. The ability to select responses therefore depends on an important combination of both our ability to think, and to move. Both of these abilities are affected by ageing, making it is important for us to improve our understanding of how we learn to select responses, understand how this is affected by ageing, and identify ways in which we could improve our ability to select appropriate responses. The overall objectives of this project are to measure the problems that older adults have when attempting to select appropriate responses, to develop new approaches to improve our ability to select responses, to identify the regions of the brain that are involved in action selection tasks, and to learn whether the ability to select responses can be predicted by combining data from performing action selection tasks with data from scans of the brain. Based on the findings of the project, we are able to conclude that older adults do not slow down to favour accuracy - the slowing of their actions is part of a general age-related reduction in performance, that we can enhance the rate of learning using novel training paradigms developed during this project, and that a cerebellar-cortico network underlies behavioural response selection.
Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз
Цел на проекта
This multidisciplinary proposal combines behavioural science, neuroscience, and ageing research with the goal of providing an innovative, state-of-the-art approach to address age related declines in human performance.The ageing population presents unprecedented challenges for society, and developing novel approaches to understand and address age related declines is an key field for research. Response selection provides a novel and ideal model to examine the effects of ageing on behaviour. The rapid selection of appropriate responses is an essential part of our everyday lives; for example, if we see a red light while driving, it is critical that we can quickly select the correct response of braking. Such behaviour depends not only on our ability to learn to match an essentially arbitrary cue (the red light) with the required response (pushing the brake pedal), but also to automate this response through practice. Response selection thus lies at the intersection between cognitive function and movement control, both of which decline in healthy ageing; older individuals require more time to select correct movement responses even in relatively simple tasks. This fellowship will 1) broaden the scientific understanding of response selection using a novel behavioural task, 2) improve this important function in an impaired population using non-invasive brain stimulation techniques, 3) capture the underlying neural mechanisms of both deficit and improvement using a multidisciplinary combination of non-invasive brain stimulation and electroencephalography, and 4) develop biomarkers using magnetic resonance imaging and neuropsychological data to understand and predict interindividual differences.
Оригинален текст от CORDIS (на английски).
Участници
- KATHOLIEKE UNIVERSITEIT LEUVEN · LeuvenКоординаторБелгия
Връзки
Данни: CORDIS, © Европейски съюз