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КартаВръзкиТемиБългарияНощта (K-TRIO)Мария Склодовска-КюриЗа ученициЗа учителиМетодологияИзненадай ме
H2020Обмен на изследователи2017–2022

Olive-Net · Bioactive compounds from Olea europaea: investigation and application in food, cosmetic and pharmaceutical industry

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период
2017-03-01 → 2022-08-31
Финансиране от ЕС
1 732 500 €
Участници
16
Схема
MSCA-RISE

Линиите свързват координатора с партньорите.

Накратко на български

Биоактивните съединения от маслината, като хидрокситирозол и олеуропеин, се извличат от плода и листата на дървото. Те помагат за разработването на нови съставки за козметиката и фармацията, като подобряват стабилността и свойствата им при възпаления и стареене.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Bioactive compounds from Olea europaea: investigation and application in food, cosmetic and pharmaceutical industry

The olive tree is a critical agricultural element for the EU, especially for the countries of the Mediterranean region. Olive oil and fruit contain hydrophilic (phenolic acids and alcohols, flavonoids and secoiridoids) and lipophilic compounds that are known to possess multiple biological activities. The main biophenols found in the products of olive tree are hydroxytyrosol, tyrosol, oleuropein, oleacein, oleocanthal, ligstoside aglycons and verbascoside. Furthermore, the olive processing industry is responsible for the production of a huge bulk of by-products. These materials, olive leaves and olive mill side products can also be proven as innovative and efficient sources of the aforementioned olive bioactives. Olive-Net is an ambitious project based on state-of-the-art natural product chemistry and biology, in order to exploit diverse raw materials coming from the olive tree for the development of novel active ingredients that could be used in the pharmaceutical, nutraceutical and cosmetic industry. This was achieved through an extended and well-balanced scheme of researcher’s secondments between universities and enterprises from EU & Associated countries as well as universities from Third countries. The objectives will be: • Exploitation of diverse raw materials coming from the olive tree • Generation of new extraction, enrichment and isolation protocols based on emerging novel technologies dedicated to olive bioactives • Analyze the chemical content of the extracts/enriched fractions • Investigation of the chemical transformation of olive bioactive compounds (such as oleocanthal and oleaceain) in order to improve their stability and pharmacological properties • Investigation of the pharmacological properties of olive bioactives in relation to inflammation and ageing • Perform PK/PD studies of pure compounds • Development of new formulations of bioactive compounds and/or extracts for incorporation into pharmaceutical/nutraceutical/cosmeceutical products • Scale up the best extraction process • Address the demand of the consumers on natural solutions by formulating and testing new products based on plant chemical diversity.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

The goal of Olive-Net project is to introduce a novel approach for the exploration, valorization and marketing of new products based on bioactive compounds from Olea europaea. This will be achieved through an extended and well-balanced scheme of researcher’s secondments between universities and enterprises from EU & Associated countries as well as universities from Third countries. A mutual scientific project developed on the needs and interests of both sectors exploiting the existing expertise will be the base of this proposal. Products and side-products of the olive tree such as olive oil, edible olive fruits, olive mill waste and olive tree leaves, will be subjected to a series of state-of-the-art extraction and isolation cascades in order to provide extracts, enriched fractions and isolated compounds of high purity. Target chemical categories will involve the well known olive oil polyphenols and secoiridoids, that will be assessed for their safety and pharmacological effects against inflammation, osteoarthritis, cardiovascular disease, etc. in cell-based and in vivo assays. All active ingredients will be identified and characterized with advanced analytical techniques, in order to be integrated in formulations and products in the area of nutraceuticals/dietary supplements. Within this project, core scientific multidisciplinary knowledge from different research areas will be integrated creating valuable synergies. Expertise will be transferred by means of the seconded researchers training in environments with different research orientation where complimentary skills are required. Special attention will be given to dissemination activities aiming to public awareness of benefits of healthy diet(s). Olive-Net aspires to create a successful model promoting considerably researchers’ competences and long-lasting collaboration between Industry and Academia.

Оригинален текст от CORDIS (на английски).

Участници

Връзки

Данни: CORDIS, © Европейски съюз