H2020Индивидуална стипендия2018–2020

MER-CURE · Using global marine metagenomics to understand MERcury microbial associated processes: finding a CURE for mercury contaminated environments

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период: 2018-09-01 → 2020-09-30
Финансиране от ЕС: 158 122 €
Участници: 1
Схема: MSCA-IF-EF-ST

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Накратко на български

Микробите в световните океани и техните гени се анализират, за да се разбере как те трансформират и пречистват живачката. Това е важно, защото токсичният метилмеркур се натрупва в рибите, които хората консумират, застрашавайки здравето им.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Using global marine metagenomics to understand MERcury microbial associated processes: finding a CURE for mercury contaminated environments

Anthropogenic perturbations have alarmingly tripled the mercury content of surface Earth reservoirs (atmosphere, ocean, or terrestrial) compared to pre-anthropogenic conditions. Nowadays, millions of people are exposed to harmful levels of this potent neurotoxin, concretely to the organic form methylmercury that bio-accumulates in organisms and biomagnifies in marine food webs. Understanding mercury transformations within the oceanic water column remains a critical issue because fish harvested for commercial use originates largely from marine ecosystems, and are a primary source of methylmercury to humans globally. The overall aim of MER-cURE in to describe microbial populations involved in Hg processes in the marine environments at a global ocean scale. The specific objectives are: 1. To identify key microbial prokaryotic populations involved in Hg processes (containing hgcAB and/or merAB genes) in the marine environments at a global ocean scale. 2. To provide quantitative data of the amount of MeHg and Hg that can be degraded/eliminated in the sea, thus revealing ocean hot-spots for Hg detoxification and helping to complete global oceanic Hg models. 3. To quantify Hg detoxification rates in bacterial cultures and marine contaminated sediments to develop a pilot-system for Hg removal. 4. To engage stakeholders in the management process, to develop and implement a communication strategy based on formative purposes to effectively translate and share research achievements from objectives 1 to 3.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

Millions of people are exposed to harmful levels of the potent neurotoxin mercury (Hg), concretely to the organic form methylmercury (MeHg) that bio-accumulates in organisms and biomagnifies in marine food webs. Understanding Hg transformations in the ocean is critical because commercial fish are mainly marine species. While it is well known that both MeHg formation and degradation are genetically mediated by prokaryotes, there are still sizable gaps in the fundamental understanding of the organisms and mechanisms involved in Hg transformations in the environment and therefore a clear lack of available techniques for Hg removal based on the action of these genes. MER-CURE aims at filling this gap by providing the first Hg reference gene catalogue at a global ocean scale and by quantifying the individual and/or combined effect of the activity of these genes in a pilot Hg removal system. MER-CURE develops a novel and multidisciplinary methodological approach by merging omics and Hg stable isotope tracer technologies for studying the biogeochemistry and detoxification of Hg. Concretely, the fellow will take advantage of the available sequenced metagenomes and metatranscriptomes and isolates from the Global Ocean Circunnavigation Expedition Malaspina. She will carry out laboratory conducted experiments to elucidate the capacity of different marine isolates to detoxify Hg-contaminated sediments. MER-CURE will contribute to advance knowledge by identifying “where” and “which” prokaryotes in the ocean are involved in Hg cycling and to produce readily applicable results that can in the future help municipality and private industries. MER-CURE is committed to knowledge sharing and to engage the public into the action. The incorporation of metagenomic and metatranscriptomics analyses in Dr. Bravo toolbox will lead the fellow to master a rather unique combination of chemistry, biology, experimental approaches, public engagement, and knowledge sharing and communication skills.

Оригинален текст от CORDIS (на английски).

Участници

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS · MadridКоординаторИспания