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КартаВръзкиТемиБългарияНощта (K-TRIO)Мария Склодовска-КюриЗа ученициЗа учителиМетодологияИзненадай ме
H2020Докторантска мрежа2018–2022

AiPBAND · An Integrated Platform for Developing Brain Cancer Diagnostic Techniques

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период
2018-01-01 → 2022-06-30
Финансиране от ЕС
3 687 312 €
Участници
20
Схема
MSCA-ITN

Линиите свързват координатора с партньорите.

Накратко на български

Диагностичните техники за откриване на рак на мозъка, като при глиома и глайобластома, са в центъра на този проект. По-ранното и точното разпознаване на тези тумори помага за подобряване на стратегиите за лечение и грижа за пациентите.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

An Integrated Platform for Developing Brain Cancer Diagnostic Techniques

AiPBAND started on January 1, 2018 until June 30th, 2022 including 6 month Covid-19 extension. The project consortium consisted of 13 beneficiaries (10 academic institutes, 3 SMEs) from 5 European countries and aimed to train 14 ESRs in developing brain cancer diagnostic techniques. Gliomas are the most common primary intracranial tumour, accounting for 81% of malignant brain tumours and although relatively rare, cause significant mortality and morbidity. About 45% of all gliomas are Glioblastoma (GBM) and is the most common histology with a 5-year relative survival of about 5%. Although adjuvant therapies, such as radiotherapy and chemotherapy are applicable and can prolong survival, GBM usually has a poor prognosis. Therefore, developing improved patient-oriented strategies for combating brain cancer is still one of the leading challenges faced by the EU. This ranges from prevention to more effective and earlier diagnosis, to better treatment with minimal side effects. The long-term fight against brain cancer and lack of young interdisciplinary talents in the brain cancer diagnostic field requires intensive training of a new generation of early-stage researchers (ESR’s). AiPBAND aimed to provide an excellent interdisciplinary, intersectoral and international (triple-i) research and training platform, with multidisciplinary expertise and cutting-edge technologies for developing innovative diagnostic techniques for brain cancer. Through this platform ESRs were trained to maximize their potential of knowledge transformation, employability, and becoming future leaders in both academia and industry. AiPBAND brought together leading academic and industrial experts from four major consortia in Europe, their synergies enhance strongly the cross-sectoral participation and contribution to the research and training.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

The mission of AiPBAND is to train a new generation of entrepreneurial and innovative early-stage researchers (ESRs) in the early diagnosis of brain tumours using molecular biomarkers in the blood, meeting the medical and societal challenges of this emerging field. AiPBAND will focus on gliomas, a range of devastating and progressive brain tumours affecting around 25,000 people each year in Europe and responsible for the majority of deaths from primary brain tumours.Fourteen fellows will be trained by experts in 9 academic and 3 non-academic beneficiaries, belonging to 5 EU member states and 6 partner organizations (4 private sectors and 2 international academic), with fields ranging from neuroscience, engineering (including big data science), healthcare to economics. State-of-the-art technologies will be applied in parallel to (i) identify novel blood biomarkers from patients with gliomas, (ii) design three types of multiplex biosensor (plasmonic-based, graphene-based, and digital ELISA assay-based), (iii) develop a big data-empowered intelligent data management infrastructure, and (iv) develop cloud-based diagnostic systems. Proof-of-concept will be evaluated through clinical trials to assess accuracy, sensitivity and specificity. The elaborately designed individual research projects under the Vitae Researcher Development Framework – carefully arranged into local training courses, network wide events, secondments, personalized career development plans, with strong involvement of the private sector – will ensure exploitation of AiPBAND's achievements, and will maximize the ESRs’ abilities in creative & innovative thinking, triple-i knowledge transformation, and encourage a business-orientated mind-set and entrepreneurship.

Оригинален текст от CORDIS (на английски).

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Данни: CORDIS, © Европейски съюз