Меню
КартаВръзкиТемиБългарияНощта (K-TRIO)Мария Склодовска-КюриЗа ученициЗа учителиМетодологияИзненадай ме
H2020Докторантска мрежа2017–2022

DRIVE · Driving next generation autophagy researchers towards translation

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период
2017-11-01 → 2022-04-30
Финансиране от ЕС
3 890 065 €
Участници
35
Схема
MSCA-ITN

Линиите свързват координатора с партньорите.

Накратко на български

Автофагията и нейните механизми се изследват, за да се създадат модели и биомаркери за следене на процеса при рак и инфекции. Това помага за превръщането на фундаменталните научни знания в продукти за здравеопазването и по-ефективни терапии.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Driving next generation autophagy researchers towards translation

The manipulation of autophagy has an enormous therapeutic potential to revolutionize the way we currently treat cancers, neurodegenerative disorders, inflammatory and infectious diseases. Knowledge about the mechanism and regulation of autophagy is growing at a breakneck speed. However, translation of this knowledge into clinical-grade products with a benefit for the public healthcare has lagged behind. Translation is currently hampered by the lack of knowledge about the precise contribution of autophagy for different physiological and pathological situations, but also by the lack of models and biomarkers and assays to monitor autophagy in vivo. This gap does not allow to effectively test therapies and drugs and hampers the realization of clinical trials. Moreover, despite the great promises made by pioneering medical studies, the still limited applied research on autophagy has hampered the translation of fundamental knowledge into clinical-grade products and improved healthcare. Applied autophagy research is essential to understand the roles of autophagy in the different physiological and pathological situations, to generate (disease) models and develop biomarkers and assays to assess its progress. The ultimate goal of the ETN Driving next generation autophagy researchers towards translation (DRIVE) has been to train 15 young scientists through a tailored program, to fill these two gaps. Each one of them has realized a cutting-edge project in either an academic research group or company.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

The manipulation of autophagy has an enormous therapeutic potential to revolutionize the way we currently treat cancers, neurodegenerative disorders, inflammatory and infectious diseases. Despite the great promises made by pioneering medical studies, the still limited applied research on autophagy has hampered the translation of fundamental knowledge into clinical-grade products and improved healthcare. Applied autophagy research is essential to understand the roles of autophagy in the different physiological and pathological situations, to generate (disease) models and develop biomarkers and assays to assess its progress.The goal of the ETN Driving next generation autophagy researchers towards translation (DRIVE) is to train young scientists to fill this gap. DRIVE will equip its ESRs with an unique combination of knowledge and experimental expertise that are brought together in this consortium by the different partners. The realization of their projects in applied autophagy research will benefit of an exceptional interdisciplinary platform integrating cell biology, biochemistry, molecular biology, genetics, chemistry and “omics” approaches. In addition, DRIVE ESRs will acquire competencies to exploit the results for the development of products and techniques of commercial value. These ESRs will also be trained in disseminating results and knowledge through modern channels of communication.

Оригинален текст от CORDIS (на английски).

Участници

Връзки

Данни: CORDIS, © Европейски съюз