H2020Обмен на изследователи2018–2023

CanBioSe · Novel 1D photonic metal oxide nanostructures for early stage cancer detection

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период: 2018-01-01 → 2023-12-31
Финансиране от ЕС: 1 116 000 €
Участници: 15
Схема: MSCA-RISE

Линиите свързват координатора с партньорите. За проекти отпреди 2014 г. CORDIS не винаги дава точни координати. Тези точки са на ниво град или държава.

Накратко на български

Наноструктури от метални оксиди и антитела се използват за създаване на преносим биосензор за откриване на ракови клетки. Ранната диагностика на рака помага за справянето с един от важните проблеми със здравето в обществото на ЕС.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Novel 1D photonic metal oxide nanostructures for early stage cancer detection

The CanBioSe project research and innovation goals are targeted to develop a new portable tool for early stage cancer detection which can solve one of the important health challenges in EU society. The project is targeted to strengthen international and intersectoral collaboration, sharing new ideas, knowledge transfer from research to market, and vice versa in the field of nanostructured metal oxide optical biosensors for cancer cell detection. The project partners will provide research and training activities in the fields of nanotechnology, surface functionalization, bioengineering, microfluidics and biosensor testing, market analysis and commercialisation. The provided research and management training to experienced researchers and early stage researchers will be quite beneficial. It will strengthen their personal skills and CVs via the new scientific papers and conference theses and strengthen a development of EU research human resources. We foresee a long lasting collaboration between the partners, based on co-supervising students and the preparation of novel collaborative project proposals. Also foreseen is a dissemination of the project results to the scientific society and wide auditories. Scientific work will include: One dimensional (1D) polimer nanofibers will be deposited by an electrospinning technique. Photonic nanomaterials, based on metal oxide based nanostructures (ZnO, ZnO/Al2O3 nanolaminates, Au/ZnO and ZnO/Au) will coat the 1D nanofibers. Metal oxides and Au nanoparticles will be deposited with Atomic Layer Deposition (ALD) and electrophoresis, respectively. Bioselective layer will be formed by immobilization of specific antibodies on the biosensor surface. Photoluminescence and optical spectroscopy will be used for recording the biosensor signal. Biosensor testing will be performed on cancer cells (human chronic lymphocyte leukemia (CLL) leucosis and acute lymphoblastic leucosis). The biosensor will be integrated with microfluidic system in order to minimize dimensions and simplify the use of the detection system.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

The project CanBioSe targeted to strengthen international and intersectoral collaboration, sharing new ideas andknowledge transfer from research to market and vice versa in the field of nanostructured metal oxide optical biosensors forcancer cells detection. Interdisciplinary project research and innovation goals are targeted to develop a new portable tool forearly stage cancer detection which can solve on of important health challenges in EU society. One dimensional (1D) polimernanofibers will be deposited by electrospinning technique. Photonic nanomaterials, based on metal oxide basednanostructures (ZnO, ZnO/Al2O3 nanolaminates, Au/ZnO and ZnO/Au) will coat the 1D nanofibers. Metal oxides and Aunanoparticles will be deposited with Atomic Layer Deposition (ALD) and electrophoresis, respectively. Bioselective layer willbe formed by immobilization of specific antibodies on the biosensor surface. Photoluminescence and optical spectroscopywill be used for recording of the biosensor signal. Biosensor testing will be performed on cancer cells (human chroniclymphocyte leukemia (CLL) leucosis and acute lymphoblastic leucosis). The biosensor will be integrated with microfluidicsystem in order to minimize dimensions and simplify the use of the detection system.The project partners will provide research and training activities in the fields of nanotechnology, surface functionalization,bioengineering, microfluidics and biosensor testing, market analysis and commercialization. Provided research andmanagement training to experienced researchers and early stage researchers will strengthen their personal skills and CVsvia new scientific papers and conference theses and strengthen a development of EU research human resources. Longlasting collaboration between partners, based on co-supervising students and preparation of novel collaborative projectproposals is foreseen. Dissemination of the project results to scientific society and wide auditories is foreseen.

Оригинален текст от CORDIS (на английски).

Участници

LATVIJAS UNIVERSITATE · RIGAКоординаторЛатвия
3D STRONG, SIA · UlbrokaЛатвия
BIOSENSOR SRL · FormelloИталия
CSD HEALTH CARE · KYIVУкрайна
ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER · MONTPELLIER CEDEX 5Франция
EESTI MATERJALITEHNOLOOGIATE ARENDUSKESKUSE OÜ · TartuНиво градЕстония
FONDAZIONE BRUNO KESSLER · TrentoИталия
Institute of Biophysics and Cell Engineering, National Academy of Sciences of Belarus · MinskНиво градБеларус
MATERIALS RESEARCH CENTER · KievУкрайна
MB SENSOGRAFA · VilniusЛитва
NANO PRIME SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA · DEBICAПолша
NANOPHARMA AS · PardubiceЧехия
STATE INSTITUTION REPUBLICAN SCIENTIFIC AND PRACTICAL CENTER FOR TRANSFUSIOLOGY AND MEDICAL BIOTECHNOLOGIES · MINSKНиво градБеларус
UNIWERSYTET IM. ADAMA MICKIEWICZA WPOZNANIU · PoznanПолша
VILNIAUS UNIVERSITETAS · VilniusЛитва