CHROMREP · An integrative approach linking chromosomal evolution and biodiversity in reptiles from Madagascar
„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“
- Период
- 2018-10-01 → 2020-09-30
- Финансиране от ЕС
- 183 455 €
- Участници
- 1
- Схема
- MSCA-IF-EF-ST
Линиите свързват координатора с партньорите.
Накратко на български
Еволюцията на хромозомите при влечугите в Мадагаскар се анализира чрез промени в техния брой и форма. Това помага да се разбере как тези генетични трансформации влияят върху появата на нови видове и разпределението им в природата.
Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.
Резултати накратко
An integrative approach linking chromosomal evolution and biodiversity in reptiles from Madagascar
Chromosomal evolution is a major, yet under-explored, driver of biodiversity. Changes in chromosome number and morphology influence the generation of new biological diversity, via polyploidization and the accumulation of different chromosome rearrangements. Karyological evolution may also drive the generation of different genetic sex determination systems, via the gain or loss of heterogametic sex chromosomes. These changes can reduce or eliminate recombination with conspecifics and thus generate potential for assortative mating and ultimately speciation and reproductive compatibility in sexually reproducing organisms. Despite these factors, there are few studies that directly test for the impact of chromosome evolution on phylogenetic and biogeographic diversification in animals. To better understand processes and mechanisms of chromosomal evolutionary dynamics and to test for the influence of chromosome evolution on animal biodiversity, phylogeny and biogeography CHROMREP employs a multidisciplinary and comparative approach by examining an integrative dataset generated from multiple lineages of reptiles from Madagascar, a unique model region to study biological diversity.
Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз
Цел на проекта
Chromosomal evolution is a major, yet under-explored, driver of biodiversity. Changes in chromosome number and morphology influence reproductive compatibility in sexually reproducing organisms. Despite this, links between chromosomal changes and phylogenetic and biogeographic diversification have rarely been investigated in animals. By using an unprecedented multidisciplinary and comparative approach CHROMREP will test for the influence of chromosome evolution on the generation of animal biodiversity, phylogeny and biogeography. Specifically, employing novel combinations of cutting-edge methods on comprehensively sampled data from eight Malagasy reptile evolutionary lineages, I will perform: (a) cytogenetic analyses to provide the first comprehensive karyological assessment of the study taxa, (b) DNA sequencing and phylogenetic analyses to produce novel molecular phylogenies of each group, (c) computational analyses with phylogenetic comparative methods and statistical biogeography to test for phylogenetic, biogeographic and ecological correlates of chromosomal evolution. Explaining chromosome evolution within endemic reptile radiations of Madagascar will be a major step towards understanding the ultimate causes of speciation and lineage diversification in vertebrates. CHROMREP will help to elucidate timings and mechanisms of the evolution of the extraordinary Malagasy biodiversity, statistically evaluating distinct scenarios. The combination of a world class reptile collection, outstanding laboratory facilities and the resident researchers’ scientific expertise make the NHM the perfect setting for CHROMREP. The realization of this project would establish me as an innovative leader in the field of evolutionary biology, critically enhancing my professional skill set and reinforcing my position in the international scientific community.
Оригинален текст от CORDIS (на английски).
Участници
- NATURAL HISTORY MUSEUM · LondonКоординаторОбединеното кралство
Връзки
Данни: CORDIS, © Европейски съюз