H2020Индивидуална стипендия2019–2021

DCMeta · Dual Catalysis for Meta Functionalisation under Mild Conditions

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период
2019-02-01 → 2021-01-31
Финансиране от ЕС
183 455 €
Участници
1
Схема
MSCA-IF

Линиите свързват координатора с партньорите.

Накратко на български

Видимата светлина се използва за активиране на метални катализатори, за да се създават нови химични връзки при умерени условия. Това помага за по-ефективното синтезиране на молекули, използвани в медицината, земеделието и инженерството.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Dual Catalysis for Meta Functionalisation under Mild Conditions

DCMeta is a catalysis project that has examined the role of visible light in activating metal catalysts for new chemical transformations. The use of high energy UV light to enable chemical reactions has a long history in organic chemistry, enabling a large number of chemical reactions to proceed that are not feasible under any other method. The high energy implicit in UV photochemistry, however, along with attendant issues of specialised equipment and difficulties in scale-up, have hindered wider exploitation in industry for the synthesis of valuable molecules. Recent developments using visible light have created an exciting alternative, where simple light sources can be used in conjunction with a catalyst to enable new chemical reactivity. The synthesis of new molecules under sustainable conditions has enormous importance in our society: DNA, sugars, proteins, the molecules of nature, drugs, insecticides and vitamins represent just some of the classes of molecule essential to the way we live our lives. As a result, the discovery of new and improved ways to synthesise new and improved molecules is at the forefront of modern chemistry research. The use of metal catalysis and photochemistry offers substantial improvements to both the synthesis of existing molecules and the discovery of new ones, which can have wide application in medicine, engineering and agriculture. The overall objective is to harness visible light to control the behaviour of metal catalysts in chemical reactions.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

The proposal aims to integrate visible light photoredox catalysis with metal catalysed C-H functionalisation processes, with an emphasis on meta functionalisations under ruthenium catalysis. This dual catalysis approach will offer a very direct approach to addressing C-H bonds that are hard to manipulate under standard conditions. By using photoredox catalysis to control the electon transfer events that govern the metal catalytic cycle, we hope to establish new reactivity under mild conditions, that can be widely exploited in chemical synthesis. The first part of this proposal sets out our strategy to achieve this using substrates with covalently attached directing groups. We then want to advance further and develop ways of direct C-H activation using directing groups that can be installed in situ, which is described in the second part of the proposal.

Оригинален текст от CORDIS (на английски).

Участници

Връзки

Данни: CORDIS, © Европейски съюз