H2020Индивидуална стипендия2019–2021

EmBd · Unravelling the molecular mechanisms of monocot embryogenesis

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период: 2019-09-01 → 2021-08-31
Финансиране от ЕС: 165 599 €
Участници: 1
Схема: MSCA-IF

Линиите свързват координатора с партньорите.

Накратко на български

Молекулярните механизми на развитие на зародиша при еднозасемениката се изучават чрез моделната трева Brachypodium distachyon. Това помага да се разбере как се формират тъканите и органите при тези растения и каква е разликата им от двузасемениката.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Unravelling the molecular mechanisms of monocot embryogenesis

One key question in plant biology is how a single-celled zygote develops into a functional organism consisting of different tissues and organs. Knowledge on axis formation and meristem specification during embryogenesis in plants has tremendously advanced in the last two decades having adopted the dicot plant Arabidopsis thaliana as a model organism. The mature seeds of monocot plants display dramatic different structures than those of dicot plants. However, how these structures are patterned during embryogenesis is largely unknown. Thus, while much has been learnt from studying Arabidopsis embryogenesis, it is currently not clear if any concepts can be directly transposed to monocot embryogenesis. This underlines the urgency to study monocot embryogenesis. We took a monocot grass, Brachypodium distachyon as a model to systematically study monocot embryogenesis, especially for understanding early patterning events, such as formation of the primary axis and specification of the meristem. This will greatly increase our knowledge on tissue specification and organ formation in monocots and broaden our understanding of the biological diversity of plant early development. In addition, it will provide the basis for future investigation of crucial genetic interactions between individual seed compartments (seed coat, embryo, and endosperms).

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

One key question in developmental biology is how a single-celled zygote develops into a functional organism consisting of different organs and tissues during embryogenesis. Knowledge about embryogenesis in plants has been tremendously advanced in the last two decades after adopting the dicot plant Arabidopsis thaliana as a model organism. Auxin and WUSCHEL_RELATED_HOMEOBOX transcription factors have been shown to play essential roles in patterning such as apical-basal axis formation and meristems initiation. However, how the embryo of monocot plants develops is still mostly unknown, although monocot grasses encompass the world’s most important food, feed and bioenergy crops. Compared to dicot embryo development, monocot embryogenesis has its own unique features, such as unpredictable cell division, monocotyledon and a root originated from embryo center. While much has been discovered by studying Arabidopsis embryogenesis, it is currently not clear if these concepts can be directly transposed to monocots. Brachypodium distachyon has recently emerged as a new monocot model species because of its clear advantages over crop model species. Thus, I propose to systematically study monocot embryogenesis using Brachypodium distachyon in the Weijers lab. By combining live imaging, modelling of key genetic interactions, transcriptome profiling, and genetics, I will try to understand how the embryo develops. I aim to reveal molecular similarities and divergence in tissue patterning between monocot and dicot embryogenesis by studying the function of auxin and WOX genes in Brachypodium, as well as discover the molecular networks that regulate the unique aspects of monocot embryogenesis. This will increase our knowledge on early patterning events critical to set up the initial body plan in monocots and the biological diversity of plant early development. In addition, this action will greatly assist me to reach scientific maturity and independence.

Оригинален текст от CORDIS (на английски).

Участници

WAGENINGEN UNIVERSITY · WageningenКоординаторНидерландия