H2020Индивидуална стипендия2018–2020

MeeLiH · Measure of the Ecological influence in Epigenetic-mediated Learning and memory formation in the Honeybee

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период: 2018-05-02 → 2020-12-16
Финансиране от ЕС: 152 653 €
Участници: 1
Схема: MSCA-IF-EF-CAR

Линиите свързват координатора с партньорите.

Накратко на български

Влиянието на пестицидите върху паметта и адаптацията на пчелите се анализира чрез промените в техните нервни клетки. Разбирането на тези процеси помага за опазване на пчелите, които са необходими за опрашването на земеделските култури.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Measure of the Ecological influence in Epigenetic-mediated Learning and memory formation in the Honeybee

During the last decade, bee populations have suffered significant losses and collapse of entire colonies has increased dramatically around the world. Many factors appeared to be responsible for the weakening of bees and particularly due to the use of insecticides in agriculture. Given the dependence of agricultural crops on pollinators, there is a strong economic interest in anticipating the widespread decline of bees. The memory and adaptation of bees are two cognitive skills that ensure the health and productivity of the colony. However, a growing number of scientific studies point toward an impairment of cognitive abilities in foragers when exposed chronically and even to low doses of pesticides from the neonicotinoid class. The difficulty in evaluating the impact of an exposure lies, in particular, in the lack of tools to evaluate the effects of pesticides under natural conditions and a limited knowledge of the fundamental mechanisms governing the molecular processes for the establishment of memory in honeybees. The main objectives of this project were to 1/ develop a methodology able to directly assess under field condition the memory and behavioural adaptation capacities of honeybees exposed to pesticide, 2/ characterize the neuronal cells involved in the epigenetic remodelling during memory formation, 3/ Validate our observations by carrying out behavioural rescue experiments to mitigate the effects of the pesticide.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

Understanding the mechanisms of species adaptation within ecosystems in perpetual change is one of the greatest contemporary scientific challenges. Pollinating insects such as honeybees are particularly sensitive to the changes brought by the intensive mono-agricultural practices and insecticide exposure. Anticipating the widespread decline of bees requires a better understanding of the molecular pathways that affect their cognition such as memory, within their natural habitats. The unique field based behavioural experiments used in this proposal will provide memory and adaptation indexes from honeybees of various ecological and geographical places in Greece. It will help monitoring bee heath, improve beekeeper practices and consequently, participate in a better pollinator European management strategy. The recent discovery of epigenetic mechanisms that can explain phenotypic plasticity of honeybee holds great promise in understanding epigenetic-mediated adaptation. This proposal will also use state-of-the-art ‘-omic’ and super-resolution microscopy techniques to determine the brain cells type associated with the epigenetic dynamic occurring during memory formation in bees. These results will greatly participate to the understanding mechanisms of brain plasticity. The multidisciplinary approach of this proposal is feasible thanks to the unique combination of the researcher expertise on epigenetic study in social insects together with the extensive competence for the characterisation of the molecular pathways involved in memory formation of the host lab. Moreover the two partner organizations and their network will bring additional expertise and infrastructure for honeybee management used in this proposal. Together, the results of this proposal will generate new health indexes for bees, molecular biomarkers to the environmental quality and will participate to a better management of pesticide for sustainable agriculture.

Оригинален текст от CORDIS (на английски).

Участници

EREVNITIKO KENTRO VIOIATRIKON EPISTIMON ALEXANDROS FLEMINGK · Vari-AthensКоординаторГърция