H2020Индивидуална стипендия2018–2020

SiBaToGA · The influence of stress in the bones and teeth of great apes

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период: 2018-09-01 → 2020-08-31
Финансиране от ЕС: 185 076 €
Участници: 1
Схема: MSCA-IF-EF-ST

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Накратко на български

Маркерите за стрес в костите и зъбите на приматите се анализират чрез изследване на асиметрията на лицето и дефекти в зъбния емайл. Резултатите помагат за опазването на животните и подобряват работата на стоматолозите и челюстно-лицевите хирурзи.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

The influence of stress in the bones and teeth of great apes

This project aimed to measure stress markers in the bones and teeth of great apes. Two studies measured the degree of asymmetry in the faces of human and nonhuman apes. Three studies characterized dental defects that form in response to stressors like malnutrition, injury, and illness during early life. The beneficiary created a method that makes three-dimensional maps of the tooth surface in order to analyze these features quantitatively, and applied it to nonhuman ape as well as human and Neanderthal teeth. Finally, this project analyzed thin sections of teeth to study their microscopic development in different species, including pigs, humans, and nonhuman great apes. Beyond biological anthropology, these results are relevant to conservationists interested in understanding how and when apes are stressed in early life, as well as clinicians, dentists, and orofacial surgeons who encounter (and correct) these features in their work. The project results will continue to be shared with the public for years to come, helping them to better understand their own anatomy and relationships with other species.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

Great ape populations are dwindling. There is an urgent need to measure the impact of stress on great ape physiology and fitness so that detrimental effects can be mitigated. The stress response is usually studied through hormone analyses in living animals, but acute episodes also leave behind a permanent record in bones and teeth. This project characterizes three separate hard tissue stress markers that reflect developmental perturbations at different life stages: facial asymmetry (in utero), dental enamel defects (early life), and dental cementum abnormalities (adulthood). This project represents the first time that these stress markers will be coinvestigated, and it does so using innovative and cutting-edge techniques. The study sample includes wild and captive great apes that were the focus of intensive monitoring during life. The associated health, behavioral, and climate data provide an unparalleled context in which stress markers can be interpreted. While these common stress markers are well understood in modern humans, never before have they been linked to particular causes in wild primates. Given our close genetic relationship, understanding stress markers in wild primates will facilitate the interpretation of the same features in human remains from fossil or historical contexts. The Applicant is an ideal candidate to conduct this multidisciplinary project as she has the necessary background knowledge and imaging expertise. The sample is almost entirely assembled and ready to analyze. She will receive training-through-research to dramatically expand her expertise to include analytical techniques that are foundational to her field (i.e., 3D geometric morphometrics) as well as new and highly-specialized confocal profilometry- and histology-based methods. This project will mutually benefit from its close association with the CemeNTAA Project led by Supervisor Dr. Rendu which aims to develop and refine methods used to study dental cementum.

Оригинален текст от CORDIS (на английски).

Участници

UNIVERSITE DE BORDEAUX · BordeauxКоординаторФранция