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H2020Докторантска мрежа2018–2023

ASCTN-Training · Training on Advanced Stem Cell Technologies in Neurology

„Хоризонт 2020“ — Действия „Мария Склодовска-Кюри“

Период
2018-10-01 → 2023-03-31
Финансиране от ЕС
3 749 403 €
Участници
11
Схема
MSCA-ITN

Линиите свързват координатора с партньорите.

Накратко на български

Стволовите клетки се използват за моделиране на неврологични заболявания като болестите на Паркинсон и Хънтингтън. Това помага за по-доброто разбиране на тези състояния и разработването на нови лекарства за тяхното лечение.

Този кратък обзор е генериран от изкуствен интелект

Кратко обяснение, генерирано от езиков модел по текста на CORDIS. Оригиналът е по-долу.

Резултати накратко

Training on Advanced Stem Cell Technologies in Neurology

ASCTN-Training was addressing existing gaps within stem cell-based technologies to study Neurological Disorders (e.g. Parkinson´s, Huntington's and Demyelination’s diseases), including the modelling of these devastating diseases to develop new medicines for their treatments. Neurological Disorders occur because of the acute or progressive loss of brain cells, structures, and functions in the brain. They have a high prevalence and are associated with short- and long-term impairments and disabilities with a high emotional, financial, and social burden on the patients, their families, and their social network. Neurodegenerative diseases are mostly incurable and affect millions of people. In addition to the suffering, these diseases have a gigantic economic impact, calculated to be higher than 130 billion € per year in Europe. To decrease human suffering and reduce costs to society, new scientific discoveries and technologies are urgently needed. The main objective of ASCTN-Training was to train a new generation of 14 highly inter-disciplinary early-stage researchers, capable of mastering techniques and methods across the borders of their own disciplines and recognizing ideas applicable to their own work. During that period, the early-stage researchers were involved in mimicking the neurodegenerative disease, both physiologically and anatomically, study cell-cell and cell tissue interactions, stablishing cell differentiation protocols, and characterizing all the studies. In general, all these studies carried out by early-stage researchers allowed for improvements in the current strategies to properly reproduce the neurological disorders and thus better characterize them.

Текст от CORDIS, на английски · Данни: CORDIS, © Европейски съюз

Цел на проекта

Neuronal disorders (NDs) are associated with behavioural and cognitive impairments and have a high prevalence. As such they are a high emotional, financial and social burden on the patients and their social network. To reduce the impact of NDs new scientific technologies and disease models must be developed, and specialized professionals are needed. The primary aim of ASCTN-Training is to provide the appropriate training for the participating ESRs, so that each individual ESR will complete a PhD degree based on their research work, while at the same time equipping them with the necessary tools to collaborate and develop innovative technologies for the modeling of NDs and the development of novel therapiesASCTN-Training consists of six closely interlinked Work Packages (WPs), the central theme – techniques for modeling neuronal disorders - will be executed through scientific WPs 1-3 – biotechnology, molecular neurobiology and preclinical studies - where individual ESRs will be trained together across multiple scientific disciplines. Training will be achieved using the different didactic methods in WP4 – education and training - to enable efficient work on each ESR project as well as in joint efforts with other ESRs both within and across WPs1-3. Each ESR project is directly or indirectly linked to other ESR projects and contributes various parts to the different scientific WPs, which in turn will make a large contribution to the completion of the scientific deliverables. The education, training and industrial secondments will provide ESRs with training in both individual scientific disciplines and inter-disciplinary fields. This approach will provide ESRs with the transferrable inter-sectorial skills and tools that will prepare them for innovative thinking and true inter-disciplinary work. Communication, dissemination and exploitation of the results that are obtained will be achieved through WP5 while ASCTN-Training as a whole will be managed through WP6.

Оригинален текст от CORDIS (на английски).

Участници

Връзки

Данни: CORDIS, © Европейски съюз